Hydrothermal synthesis of carbon nanodots from wine cork and biocompatible fluorescent probe

Ngo Khoa Quang; Nguyen Ngoc Hieu; Vo Van Quoc Bao; Vo Thi Phuoc; Le Xuan Diem Ngoc; Luong Quang Doc; Nguyen Minh Tri; Le Vu Truong Son; Le Van Thanh Son; Che Thi Cam Ha

doi:10.3762/bxiv.2021.45.v1

Hydrothermal synthesis of carbon nanodots from wine cork and biocompatible fluorescent probe

Ngo Khoa Quang ,
Nguyen Ngoc Hieu ,
Vo Van Quoc Bao ,
Vo Thi Phuoc ,
Le Xuan Diem Ngoc ,
Luong Quang Doc ,
Nguyen Minh Tri ,
Le Vu Truong Son ,
Le Van Thanh Son and
Che Thi Cam Ha

Submitting author affiliation:

University of Sciences, Hue University, Hue, Viet Nam

Beilstein Arch. 2021, 202145. https://doi.org/10.3762/bxiv.2021.45.v1

Published 09 Jun 2021

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Read the peer-reviewed version of this preprint: http://xxtcl.sxicc.ac.cn/en/article/doi/10.1016/S1872-5805(22)60608-5

SUBJECT AREAS

Show All Preprints Nanotechnology Organic chemistry Bioorganic chemistry / chemical biology Catalysis Chemical methods and reactions Flow and process chemistry Green and sustainable chemistry Materials chemistry Medicinal and pharmaceutical chemistry Nano- and molecular-scale electronics Nano-biomaterials and bioscience Nanomagnetics Nanomaterials, thin films and nanointerfaces Nanomedicine Nanometrology and nanomechanics Nano-optics Nanopatterning, self-assembly and nanofabrication Nanostructures for energy and sensing applications Natural products chemistry Organo main group chemistry Other nanotechnology (unclassified) Other organic chemistry (unclassified) Photochemistry and photovoltaics Physical organic chemistry Supramolecular chemistry

Abstract

We presented a low-cost and simple method to synthesize carbon nanodots (CDs) from waste wine cork using hydrothermal synthesis. The structural and optical properties of the CDs are characterized by TEM, FTIR, Raman, UV-Vis absorption, and photoluminescence (PL) spectra. The analysis results indicated the average diameter of CDs ⁓ 6.2 ± 2.7 nm. Optical measurements showed the phenomenon of excitation-dependent PL and the formation of functional groups on the surface of the particles. CDs with a quantum yield of 1.54% was calculated using quinine sulfate as reference. Furthermore, a probe of wine cork-derived CDs in bioimaging has been successfully applied in living mesenchymal stem cells (MSCs). After treatment with CDs, MSCs exhibited fluorescence including green, yellow, and red colors under the excitation wavelengths in the range 330–385 nm, 450–480 nm, and 510–550 nm, respectively. The achievement demonstrated potential applications of fluorescent CDs in the field of the fluorescent image.

Keywords: carbon nanodots; hydrothermal synthesis; fluorescence; fluorescent image; waste wine cork

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When a peer-reviewed version of this preprint is available, this information will be updated in the information box above. If no peer-reviewed version is available, please cite this preprint using the following information:

Khoa Quang, N.; Hieu, N. N.; Bao, V. V. Q.; Phuoc, V. T.; Ngoc, L. X. D.; Doc, L. Q.; Tri, N. M.; Son, L. V. T.; Son, L. V. T.; Ha, C. T. C. Beilstein Arch. 2021, 202145. doi:10.3762/bxiv.2021.45.v1

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aromatic	the word “aromatic”
aromatic aldehyde	the word “aromatic” OR “aldehyde”
+aromatic +aldehyde	both words “aromatic” AND “aldehyde”
+aromatic -aldehyde	the word “aromatic” but NOT “aldehyde”
“aromatic aldehyde”	the exact phrase “aromatic aldehyde”
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benz*yl	words that begin with “benz” and end with “yl”, such as “benzyl” or “benzoyl”
benzyl~	words that are close to the word “benzyl”, such as “benzoyl” (i.e., fuzzy search)