The chemoenzymatic synthesis of clofarabine and related 2′-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition by E. coli nucleoside phosphorylases

Ilja V. Fateev, Konstantin V. Antonov, Irina D. Konstantinova, Tatyana I. Muravyova, Frank Seela, Roman S. Esipov, Anatoly I. Miroshnikov and Igor A. Mikhailopulo
Beilstein J. Org. Chem. 2014, 10, 1657–1669. https://doi.org/10.3762/bjoc.10.173

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The chemoenzymatic synthesis of clofarabine and related 2′-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition by E. coli nucleoside phosphorylases
Ilja V. Fateev, Konstantin V. Antonov, Irina D. Konstantinova, Tatyana I. Muravyova, Frank Seela, Roman S. Esipov, Anatoly I. Miroshnikov and Igor A. Mikhailopulo
Beilstein J. Org. Chem. 2014, 10, 1657–1669. https://doi.org/10.3762/bjoc.10.173

How to Cite

Fateev, I. V.; Antonov, K. V.; Konstantinova, I. D.; Muravyova, T. I.; Seela, F.; Esipov, R. S.; Miroshnikov, A. I.; Mikhailopulo, I. A. Beilstein J. Org. Chem. 2014, 10, 1657–1669. doi:10.3762/bjoc.10.173

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Patents

  • ZABUDKIN ALEXANDER; MATVIENKO VICTOR; MATVIIENKO IAROSLAV; SYPCHENKO VOLODYMYR. Method for the synthesis of clofarabine. US 10030043 B2, July 24, 2018.
  • ザブドキン アレキサンドル; マトヴィエンコ ヴィクトル; マトヴィイエンコ イアロスラヴ; シプチェンコ ヴォロディームィル. クロファラビンの合成方法. JP 2017513884 A, June 1, 2017.
  • ZABUDKIN ALEXANDER; MATVIENKO VICTOR; MATVIIENKO IAROSLAV; SYPCHENKO VOLODYMYR. METHOD FOR THE SYNTHESIS OF CLOFARABINE. WO 2015162175 A1, Oct 29, 2015.
  • ZABUDKIN ALEXANDER; MATVIENKO VICTOR; MATVIIENKO IAROSLAV; SYPCHENKO VOLODYMYR. Method for the synthesis of clofarabine. EP 2937420 A1, Oct 28, 2015.
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