Chromatographically separable rotamers of an unhindered amide

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• Chauthe, S. K.; Sidduri, P.; Reddy, M.; Sistla, R.; Byri, V.; Uttaravalli, M. D.; Botlagunta, M.; Kumar, H.; Gupta, A.; Gupta, A. K.; Bajpai, L.; Bagadi, M.; Mathur, A. RP-HPLC separation of interconvertible rotamers of a 5-tetrahydroisoquinolin-6-yl-pyridin-3-yl acetic acid derivative and confirmation by VT NMR and DFT study. Journal of pharmaceutical and biomedical analysis 2022, 212, 114675. doi:10.1016/j.jpba.2022.114675
• Lv, J.; Li, Z.-H.; Deng, A.-J.; Qin, H.-L. A unified total synthesis of benzo[d][1,3]dioxole-type benzylisoquinoline alkaloids of aporphines, coptisines, and dibenzopyrrocolines. Organic & biomolecular chemistry 2022, 20, 658–666. doi:10.1039/d1ob02258j
• Lewin, A. H.; Silinski, P. Handling and Analysis of 5-Formyl-, 5,10-Methenyl-, 10-Formyl-, 5-Formimno-, and 5,10-Methylenetetrahydrofolates. Methods in molecular biology (Clifton, N.J.) 2019, 1996, 75–94. doi:10.1007/978-1-4939-9488-5_8
• Van Beek, W. E.; Weemaes, K.; Herrebout, W. A.; Velde, C. M. L. V.; Tehrani, K. A. Synthesis of 1-Aza-6,7-dehydrotropanes via Copper(I)-Catalyzed Coupling of 5-Chloropentan-2-one with Hydrazines and Terminal Alkynes. Synlett 2018, 29, 2643–2647. doi:10.1055/s-0037-1611041
• Gamov, G. A.; Aleksandriiskii, V. V.; Sharnin, V. A. Inhibited rotation of amide group around CN bond of nicotinamide in different solvents by 1H NMR data. Journal of Molecular Liquids 2017, 231, 238–241. doi:10.1016/j.molliq.2017.01.078
• Maddirala, A. R.; Andreana, P. R. Synthesis of 3-Substituted 2-Indol­inones by a Multicomponent Coupling Isocyanide-Dependent Microwave-Assisted Intramolecular Transamidation Process. European Journal of Organic Chemistry 2015, 2016, 196–209. doi:10.1002/ejoc.201501273
• Walz, S.; Weis, S.; Franz, M.; Rominger, F.; Trapp, O. Investigation of the enantiomerization barriers of the phthalimidone derivatives EM12 and lenalidomide by dynamic electrokinetic chromatography. Electrophoresis 2015, 36, 796–804. doi:10.1002/elps.201400499
• Čechová, L.; Procházková, E.; Císařová, I.; Dračínský, M.; Janeba, Z. Separation of planar rotamers through intramolecular hydrogen bonding in polysubstituted 5-nitrosopyrimidines. Chemical communications (Cambridge, England) 2014, 50, 14892–14895. doi:10.1039/c4cc06978a
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