Conformational analysis of 2,2-difluoroethylamine hydrochloride: double gauche effect

Josué M. Silla, Claudimar J. Duarte, Rodrigo A. Cormanich, Roberto Rittner and Matheus P. Freitas
Beilstein J. Org. Chem. 2014, 10, 877–882. https://doi.org/10.3762/bjoc.10.84

Supporting Information

Supporting Information File 1: 1H NMR spectrum of 2.
Format: PDF Size: 245.2 KB Download

Cite the Following Article

Conformational analysis of 2,2-difluoroethylamine hydrochloride: double gauche effect
Josué M. Silla, Claudimar J. Duarte, Rodrigo A. Cormanich, Roberto Rittner and Matheus P. Freitas
Beilstein J. Org. Chem. 2014, 10, 877–882. https://doi.org/10.3762/bjoc.10.84

How to Cite

Silla, J. M.; Duarte, C. J.; Cormanich, R. A.; Rittner, R.; Freitas, M. P. Beilstein J. Org. Chem. 2014, 10, 877–882. doi:10.3762/bjoc.10.84

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Marych, D.; Bilenko, V.; Ilchuk, Y. V.; Kinakh, S.; Soloviov, V.; Yatsymyrskiy, A.; Liashuk, O.; Shishkina, S.; Komarov, I. V.; Grygorenko, O. O. Synthesis and physicochemical evaluation of tetrafluorinated GABA analogue. Journal of Fluorine Chemistry 2024, 277, 110307. doi:10.1016/j.jfluchem.2024.110307
  • Nishchaya, K.; Rai, V. K.; Bansode, H. Methacrylic acid as a potential monomer for molecular imprinting: A review of recent advances. Results in Materials 2023, 18, 100379. doi:10.1016/j.rinma.2023.100379
  • Martins, F. A.; Chagas, P.; Thomasi, S. S.; Oliveira, L. C. A.; Diniz, R.; Freitas, M. P. Theoretical and X-Ray Evidence of Electrostatic Phosphonium anti and gauche Effects. Chemphyschem : a European journal of chemical physics and physical chemistry 2022, 23, e202100856. doi:10.1002/cphc.202100856
  • Silva, D. R.; Daré, J. K.; Freitas, M. P. Conformational preferences of fluorine-containing agrochemicals and their implications for lipophilicity prediction. Beilstein journal of organic chemistry 2020, 16, 2469–2476. doi:10.3762/bjoc.16.200
  • Martins, F. A.; Zeoly, L. A.; Cormanich, R. A.; Freitas, M. P. Solution conformations for the flexible 1-chloro-1,1-difluoro-2-pentanol unveiled using multinuclear magnetic resonance. Tetrahedron 2018, 74, 880–883. doi:10.1016/j.tet.2018.01.008
  • Martins, F. A.; Silla, J. M.; Freitas, M. P. Conformational impact of structural modifications in 2-fluorocyclohexanone. Beilstein journal of organic chemistry 2017, 13, 1781–1787. doi:10.3762/bjoc.13.172
  • Cormanich, R. A.; O'Hagan, D.; Bühl, M. Hyperconjugation is the Source of Helicity in Perfluorinated n‐Alkanes. Angewandte Chemie (International ed. in English) 2017, 56, 7867–7870. doi:10.1002/anie.201704112
  • Cormanich, R. A.; O'Hagan, D.; Bühl, M. Hyperconjugation Is the Source of Helicity in Perfluorinatedn‐Alkanes. Angewandte Chemie 2017, 129, 7975–7978. doi:10.1002/ange.201704112
  • Andrade, L. A. F.; Freitas, M. P. Not all third-row elements experience the fluorine gauche effect: β-fluorinated organophosphorus compounds. New Journal of Chemistry 2017, 41, 11672–11678. doi:10.1039/c7nj02463k
  • de Rezende, F. M.; Andrade, L. A. F.; Freitas, M. P. Intramolecular interactions contributing for the conformational preference of bioactive diphenhydramine: Manifestation of the gauche effect. Journal of Molecular Structure 2015, 1093, 8–12. doi:10.1016/j.molstruc.2015.03.033
Other Beilstein-Institut Open Science Activities