Antioxidant potential of curcumin-related compounds studied by chemiluminescence kinetics, chain-breaking efficiencies, scavenging activity (ORAC) and DFT calculations

Adriana K. Slavova-Kazakova, Silvia E. Angelova, Timur L. Veprintsev, Petko Denev, Davide Fabbri, Maria Antonietta Dettori, Maria Kratchanova, Vladimir V. Naumov, Aleksei V. Trofimov, Rostislav F. Vasil’ev, Giovanna Delogu and Vessela D. Kancheva
Beilstein J. Org. Chem. 2015, 11, 1398–1411. https://doi.org/10.3762/bjoc.11.151

Supporting Information

Experimental data (materials, methods, instruments and procedures), structural characterization of the synthesized compounds 2, 6, 7, 9, details for the four models applied to assess the antiradical and antioxidant activities of the compounds studied.

Supporting Information File 1: Additional experimental and theoretical data.
Format: PDF Size: 463.4 KB Download

Cite the Following Article

Antioxidant potential of curcumin-related compounds studied by chemiluminescence kinetics, chain-breaking efficiencies, scavenging activity (ORAC) and DFT calculations
Adriana K. Slavova-Kazakova, Silvia E. Angelova, Timur L. Veprintsev, Petko Denev, Davide Fabbri, Maria Antonietta Dettori, Maria Kratchanova, Vladimir V. Naumov, Aleksei V. Trofimov, Rostislav F. Vasil’ev, Giovanna Delogu and Vessela D. Kancheva
Beilstein J. Org. Chem. 2015, 11, 1398–1411. https://doi.org/10.3762/bjoc.11.151

How to Cite

Slavova-Kazakova, A. K.; Angelova, S. E.; Veprintsev, T. L.; Denev, P.; Fabbri, D.; Dettori, M. A.; Kratchanova, M.; Naumov, V. V.; Trofimov, A. V.; Vasil’ev, R. F.; Delogu, G.; Kancheva, V. D. Beilstein J. Org. Chem. 2015, 11, 1398–1411. doi:10.3762/bjoc.11.151

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Mahdi, Z. H.; Alsalim, T. A.; Abdulhussein, H. A.; Majed, A. A.; Abbas, S. Synthesis, molecular docking, and anti-breast cancer study of 1-H-indol-3-Carbohydrazide and their derivatives. Results in Chemistry 2024, 11, 101762. doi:10.1016/j.rechem.2024.101762
  • Nahar, L.; Sarker, S. D. Computational phytochemistry: An overview. Computational Phytochemistry; Elsevier, 2024; pp 1–58. doi:10.1016/b978-0-443-16102-5.00015-8
  • Shen, R.; Zhao, W.; Li, X.; Liu, J.; Yang, A.; Kou, X. Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking/dynamics simulation, bioactivities evaluation, and cytoprotection. Molecular diversity 2023. doi:10.1007/s11030-023-10733-4
  • Caval, M.; Dettori, M. A.; Carta, P.; Dallocchio, R.; Dessì, A.; Marceddu, S.; Serra, P. A.; Fabbri, D.; Rocchitta, G. Sustainable Electropolymerization of Zingerone and Its C2 Symmetric Dimer for Amperometric Biosensor Films. Molecules (Basel, Switzerland) 2023, 28, 6017. doi:10.3390/molecules28166017
  • Lin, S.; Brask, J.; Munk, L.; Holck, J.; Krogh, K. B. R. M.; Meyer, A. S.; Wittrup Agger, J.; Wilkens, C. Enzymatic Cleavage of Diferuloyl Cross-Links in Corn Bran Arabinoxylan by Two Bacterial Feruloyl Esterases. Journal of agricultural and food chemistry 2022, 70, 13349–13357. doi:10.1021/acs.jafc.2c04455
  • Rusina, I. F.; Smurova, L. A.; Veprintsev, T. L. Evaluation of antiradical activity of Schiff bases. Russian Chemical Bulletin 2022, 71, 502–507. doi:10.1007/s11172-022-3440-3
  • Nasir, N. M.; Alsalim, T. A.; El-Arabey, A. A.; Abdalla, M. Anticancer, antioxidant activities and molecular docking study of thiazolidine-4-one and thiadiazol derivatives. Journal of biomolecular structure & dynamics 2022, 41, 3976–3992. doi:10.1080/07391102.2022.2060306
  • Sakurai, S.; Kawakami, Y.; Kuroki, M.; Gotoh, H. Structure–antioxidant activity (oxygen radical absorbance capacity) relationships of phenolic compounds. Structural Chemistry 2022, 33, 1055–1062. doi:10.1007/s11224-022-01920-4
  • Romodin, L. A. Chemiluminescence Detection in the Study of Free-Radical Reactions. Part 1. Acta naturae 2021, 13, 90–100. doi:10.32607/actanaturae.10912
  • Sadatsharifi, M.; Purgel, M. Radical scavenger competition of alizarin and curcumin: a mechanistic DFT study on antioxidant activity. Journal of molecular modeling 2021, 27, 166. doi:10.1007/s00894-021-04778-1
  • Slavova-Kazakova, A.; Janiak, M. A.; Sulewska, K.; Kancheva, V. D.; Karamać, M. Synergistic, additive, and antagonistic antioxidant effects in the mixtures of curcumin with (-)-epicatechin and with a green tea fraction containing (-)-epicatechin. Food chemistry 2021, 360, 129994. doi:10.1016/j.foodchem.2021.129994
  • Naumov, V. V.; Fedorova, G. F.; Vasil'ev, R. F.; Kancheva, V. D.; Veprintsev, T. L.; Trofimov, A. V.; Yablonskaya, O. I. The Mechanism of Chemiluminescence in the Thermal Decomposition of 2,2'-Azodiisobutyronitrile in a Liquid Oxygen-Containing Medium. Russian Journal of Physical Chemistry B 2021, 15, 63–67. doi:10.1134/s1990793121010243
  • Menshov, V. A.; Kancheva, V. D.; Yablonskaya, O. I.; Trofimov, A. V. Transformation of the Antioxidant Properties of Tar from Tobacco Smoke in Metabolic Processes: Model Chemiluminescence Study. Russian Journal of Physical Chemistry B 2021, 15, 108–111. doi:10.1134/s1990793121010231
  • Kancheva, V. D.; Dettori, M. A.; Fabbri, D.; Alov, P.; Angelova, S.; Slavova-Kazakova, A.; Carta, P.; Menshov, V. A.; Yablonskaya, O. I.; Trofimov, A. V.; Tsakovska, I.; Saso, L. Natural Chain-Breaking Antioxidants and Their Synthetic Analogs as Modulators of Oxidative Stress. Antioxidants (Basel, Switzerland) 2021, 10, 624. doi:10.3390/antiox10040624
  • Brborić, J.; Klisic, A.; Kotur-Stevuljevic, J.; Delogu, G.; Ackova, D. G.; Kostic, K.; Dettori, M. A.; Fabbri, D.; Carta, P.; Saso, L. Natural and natural-like polyphenol compounds: in vitro antioxidant activity and potential for therapeutic application. Archives of medical science : AMS 2021, 19, 651. doi:10.5114/aoms/135379
  • Paquin, A.; Reyes-Moreno, C.; Bérubé, G. Recent Advances in the Use of the Dimerization Strategy as a Means to Increase the Biological Potential of Natural or Synthetic Molecules. Molecules (Basel, Switzerland) 2021, 26, 2340. doi:10.3390/molecules26082340
  • Hazarika, R.; Kalita, B. Elucidating the therapeutic activity of selective curcumin analogues: DFT-based reactivity analysis. Structural Chemistry 2021, 32, 1701–1715. doi:10.1007/s11224-021-01745-7
  • Sakurai, S.; Kawakami, Y.; Kuroki, M.; Gotoh, H. Structure-antioxidant Activity (Oxygen Radical Absorbance Capacity) Relationships of Phenolic Compounds. Research Square Platform LLC 2021. doi:10.21203/rs.3.rs-180961/v1
  • de Ávila, R. M. D.; Toffano, L.; Fernandes, J. B.; da Silva, M. F. d. G. F.; de Sousa, L. R. F.; Vieira, P. C. Biotransformation of pungent constituents from ginger (Zingiber officinale Roscoe) by Colletotrichum gloeosporioides yields oxidative ortho–ortho coupling products. Biocatalysis and Biotransformation 2021, 40, 95–106. doi:10.1080/10242422.2021.1878159
  • de Ávila, R. M. D.; Toffano, L.; Fernandes, J. B.; da Silva, M. F. d. G. F.; de Sousa, L. R.; Vieira, P. C. Biotransformation of pungent constituents from ginger (Zingiber officinale Roscoe) by Colletotrichum gloeosporioides yields oxidative ortho–ortho coupling products. Biocatalysis and Biotransformation 2021, 1–12.
Other Beilstein-Institut Open Science Activities