Deproto-metallation of N-arylated pyrroles and indoles using a mixed lithium–zinc base and regioselectivity-computed CH acidity relationship

Mohamed Yacine Ameur Messaoud, Ghenia Bentabed-Ababsa, Madani Hedidi, Aïcha Derdour, Floris Chevallier, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Laurent Picot, Valérie Thiéry, Thierry Roisnel, Vincent Dorcet and Florence Mongin
Beilstein J. Org. Chem. 2015, 11, 1475–1485. https://doi.org/10.3762/bjoc.11.160

Supporting Information

Supporting Information File 1: Experimental description of the synthesized compounds, 1H and 13C NMR spectra, calculated values of the Gibbs energies ΔGacid [kcal·mo1−1] for deprotonation, selected Cartesian coordinates of molecular geometry for the most stable rotamer forms optimized at B3LYP/6-31G(d) level of theory.
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Supporting Information File 2: CIF files of 2e (CCDC1402111), 4c (1402112), 3d (1402113), 3e (1402114), and 5d (1402115). These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via http://www.ccdc.cam.ac.uk/data_request/cif.
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Cite the Following Article

Deproto-metallation of N-arylated pyrroles and indoles using a mixed lithium–zinc base and regioselectivity-computed CH acidity relationship
Mohamed Yacine Ameur Messaoud, Ghenia Bentabed-Ababsa, Madani Hedidi, Aïcha Derdour, Floris Chevallier, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Laurent Picot, Valérie Thiéry, Thierry Roisnel, Vincent Dorcet and Florence Mongin
Beilstein J. Org. Chem. 2015, 11, 1475–1485. https://doi.org/10.3762/bjoc.11.160

How to Cite

Messaoud, M. Y. A.; Bentabed-Ababsa, G.; Hedidi, M.; Derdour, A.; Chevallier, F.; Halauko, Y. S.; Ivashkevich, O. A.; Matulis, V. E.; Picot, L.; Thiéry, V.; Roisnel, T.; Dorcet, V.; Mongin, F. Beilstein J. Org. Chem. 2015, 11, 1475–1485. doi:10.3762/bjoc.11.160

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