Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates

Qinggang Mei, Chun Wang, Weicheng Yuan and Guolin Zhang
Beilstein J. Org. Chem. 2015, 11, 288–293. https://doi.org/10.3762/bjoc.11.33

Supporting Information

Supporting Information File 1: Experimental section; NMR and ESI-HRMS spectra of 1–23; NOESY spectra of 4 and 13; HMBC spectra of 4, 5, 7, 9, 12, 13, 16, 18, 22, 23.
Format: PDF Size: 9.0 MB Download

Cite the Following Article

Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates
Qinggang Mei, Chun Wang, Weicheng Yuan and Guolin Zhang
Beilstein J. Org. Chem. 2015, 11, 288–293. https://doi.org/10.3762/bjoc.11.33

How to Cite

Mei, Q.; Wang, C.; Yuan, W.; Zhang, G. Beilstein J. Org. Chem. 2015, 11, 288–293. doi:10.3762/bjoc.11.33

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Hazai, L.; Zsoldos, B.; Halmai, M.; Keglevich, P. Flavone Hybrids and Derivatives as Bioactive Agents. Applied Sciences 2024, 14, 1039. doi:10.3390/app14031039
  • Dung, N. T.; Ninh, P. T.; Luu, N. T.; Anh, N. T.; Hau, V. T. B.; Thuy, N. T. T.; Anh, H. N.; Hang, P. D.; Thao, T. T. P. Phytochemical study ofEuphorbia cyathophoracollected in Dan Phuong, Hanoi and its antidengue activity againstDENV1‐4 virus serotypes. Vietnam Journal of Chemistry 2023, 61, 371–377. doi:10.1002/vjch.202300123
  • Németh-Rieder, A.; Keglevich, P.; Hunyadi, A.; Latif, A. D.; Zupkó, I.; Hazai, L. Synthesis and In Vitro Anticancer Evaluation of Flavone-1,2,3-Triazole Hybrids. Molecules (Basel, Switzerland) 2023, 28, 626. doi:10.3390/molecules28020626
  • Kwon, J.; Hwang, H.; Selvaraj, B.; Lee, J. H.; Park, W.; Ryu, S. M.; Lee, D.; Park, J.-S.; Kim, H. S.; Lee, J. W.; Jang, D. S.; Kwon, H. C. Phenolic constituents isolated from Senna tora sprouts and their neuroprotective effects against glutamate-induced oxidative stress in HT22 and R28 cells. Bioorganic chemistry 2021, 114, 105112. doi:10.1016/j.bioorg.2021.105112
  • Wisanwattana, W.; Wongkrajang, K.; Cao, D.-Y.; Shi, X.; Zhang, Z.; Zhou, Z.; Li, F.; Mei, Q.; Wang, C.; Suksamrarn, A.; Zhang, G.; Wang, F. Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway. Frontiers in endocrinology 2021, 12, 636784. doi:10.3389/fendo.2021.636784
  • Tatsuzaki, J.; Ohwada, T.; Otani, Y.; Inagi, R.; Ishikawa, T. A simple and effective preparation of quercetin pentamethyl ether from quercetin. Beilstein journal of organic chemistry 2018, 14, 3112–3121. doi:10.3762/bjoc.14.291
  • Shen, X.; Zhou, Q.; Xiong, W.; Pu, W.; Zhang, W.; Zhang, G.; Wang, C. Synthesis of 5-subsituted flavonols via the Algar-Flynn-Oyamada (AFO) reaction: The mechanistic implication. Tetrahedron 2017, 73, 4822–4829. doi:10.1016/j.tet.2017.06.064
  • Xiao, Z.-P.; Wei, W.; Liu, Q.; Wang, P.-F.; Luo, X.; Chen, F.-Y.; Cao, Y.; Huang, H.-X.; Liu, M.-M.; Zhu, H.-L. C-7 modified flavonoids as novel tyrosyl-tRNA synthetase inhibitors. RSC Advances 2017, 7, 6193–6201. doi:10.1039/c6ra28061g
  • Mei, Q.; Wang, C.; Zhao, Z.; Yuan, W.-C.; Zhang, G. Synthesis of icariin from kaempferol through regioselective methylation and para-Claisen-Cope rearrangement. Beilstein journal of organic chemistry 2015, 11, 1220–1225. doi:10.3762/bjoc.11.135

Patents

  • DIMAURO THOMAS M. Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide. US 11304968 B2, April 19, 2022.
  • DIMAURO THOMAS M. Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite. US 10639294 B2, May 5, 2020.
Other Beilstein-Institut Open Science Activities