Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole

Scholarly Works

• Sondag, D.; Heming, J. J. A.; Löwik, D. W. P. M.; Krivosheeva, E.; Lejeune, D.; van Geffen, M.; Van't Veer, C.; van Heerde, W. L.; Beens, M. C. J.; Kuijpers, B. H. M.; Boltje, T. J.; Rutjes, F. P. J. T. Solid-Phase Synthesis of Caged Luminescent Peptides via Side Chain Anchoring. Bioconjugate chemistry 2023, 34, 2234–2242. doi:10.1021/acs.bioconjchem.3c00381
• Chang, C.-H.; Fontaine, D. M.; Gómez, S.; Branchini, B. R.; Anderson, J. C. Synthesis and Bioluminescence of 'V'-Shaped Firefly Luciferin Analogues Based on A Novel Benzobisthiazole Core. Chemistry (Weinheim an der Bergstrasse, Germany) 2023, 29, e202302204. doi:10.1002/chem.202302204
• Broudic, N.; Pacheco-Benichou, A.; Fruit, C.; Besson, T. Synthesis of 2-Cyanobenzothiazoles via Pd-Catalyzed/Cu-Assisted C-H Functionalization/Intramolecular C-S Bond Formation from N-Arylcyanothioformamides. Molecules (Basel, Switzerland) 2022, 27, 8426. doi:10.3390/molecules27238426
• Hampton, J. T.; Lalonde, T. J.; Tharp, J. M.; Kurra, Y.; Alugubelli, Y. R.; Roundy, C. M.; Hamer, G. L.; Xu, S.; Liu, W. R. Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2. ACS chemical biology 2022, 17, 2911–2922. doi:10.1021/acschembio.2c00565
• Deng, C.; Huang, J.; Qi, Y.; Chen, D.; Huang, W. Distribution patterns of rubber tire-related chemicals with particle size in road and indoor parking lot dust. The Science of the total environment 2022, 844, 157144. doi:10.1016/j.scitotenv.2022.157144
• Sondag, D.; Merx, J.; Rossing, E.; Boltje, T. J.; Löwik, D. W. P. M.; Nelissen, F. H. T.; van Geffen, M.; van 't Veer, C.; van Heerde, W. L.; Rutjes, F. P. J. T. Luminescent Assay for the Screening of SARS-CoV-2 MPro Inhibitors. Chembiochem : a European journal of chemical biology 2022, 23, e202200190. doi:10.1002/cbic.202200190
• Hu, S.; Chen, X.; Qin, X.; Dong, G.; Lin, Y.; Gai, W.; Zhao, H.; Ke, B.; Li, M. A bioluminescent probe for in vivo imaging of pyroglutamate aminopeptidase in a mouse model of inflammation. Bioorganic & medicinal chemistry letters 2021, 43, 128049. doi:10.1016/j.bmcl.2021.128049
• Pala, L.; Sirec, T.; Spitz, U. Modified Enzyme Substrates for the Detection of Bacteria: A Review. Molecules (Basel, Switzerland) 2020, 25, 3690. doi:10.3390/molecules25163690
• Bugaenko, D. I.; Karchava, A. V.; Yurovskaya, M. A. The versatility of DABCO: synthetic applications of its basic, nucleophilic, and catalytic properties. Chemistry of Heterocyclic Compounds 2020, 56, 265–278. doi:10.1007/s10593-020-02655-y
• Kovács, A. K.; Hegyes, P.; Szebeni, G. J.; Nagy, L.; Puskás, L. G.; Tóth, G. Synthesis of N-peptide-6-amino-D-luciferin Conjugates. Frontiers in chemistry 2018, 6, 120. doi:10.3389/fchem.2018.00120
• Vacher, M.; Galván, I. F.; Ding, B.-W.; Schramm, S.; Berraud-Pache, R.; Naumov, P.; Ferré, N.; Liu, Y.-J.; Navizet, I.; Roca-Sanjuán, D.; Baader, W. J.; Lindh, R. Chemi- and Bioluminescence of Cyclic Peroxides. Chemical reviews 2018, 118, 6927–6974. doi:10.1021/acs.chemrev.7b00649
• Sharma, D.; Adams, S. T.; Liebmann, K. L.; Miller, S. C. Rapid Access to a Broad Range of 6'-Substituted Firefly Luciferin Analogues Reveals Surprising Emitters and Inhibitors. Organic letters 2017, 19, 5836–5839. doi:10.1021/acs.orglett.7b02806
• Rathbun, C. M.; Prescher, J. A. Bioluminescent Probes for Imaging Biology beyond the Culture Dish. Biochemistry 2017, 56, 5178–5184. doi:10.1021/acs.biochem.7b00435
• Hauser, J. R.; Beard, H. A.; Bayana, M. E.; Jolley, K. E.; Warriner, S. L.; Bon, R. S. Economical and Scalable Synthesis of 6‐Amino‐2‐cyanobenzothiazole. ChemInform 2016, 47. doi:10.1002/chin.201650112

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