Cite the Following Article
Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents
Daniel Wiegmann, Stefan Koppermann, Marius Wirth, Giuliana Niro, Kristin Leyerer and Christian Ducho
Beilstein J. Org. Chem. 2016, 12, 769–795.
https://doi.org/10.3762/bjoc.12.77
How to Cite
Wiegmann, D.; Koppermann, S.; Wirth, M.; Niro, G.; Leyerer, K.; Ducho, C. Beilstein J. Org. Chem. 2016, 12, 769–795. doi:10.3762/bjoc.12.77
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
Picture with graphical abstract, title and authors for social media postings and presentations. | ||
Format: PNG | Size: 151.8 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Li, X.; Ju, J. Intracellularly driven chemical modifications of antimicrobial secondary metabolites: Potent mechanisms of self-resistance. Pharmaceutical Science Advances 2024, 2, 100032. doi:10.1016/j.pscia.2023.100032
- Lee, J.; Hwang, J.-Y.; Oh, D.; Oh, D.-C.; Park, H.-G.; Shin, J.; Oh, K.-B. Tunicamycins from Marine-Derived Streptomyces bacillaris Inhibit MurNAc-Pentapeptide Translocase in Staphylococcus aureus. Marine drugs 2024, 22, 293. doi:10.3390/md22070293
- Kawsar, S. M. A.; Hossain, M. A.; Saha, S.; Abdallah, E. M.; Bhat, A. R.; Ahmed, S.; Jamalis, J.; Ozeki, Y. Nucleoside‐Based Drug Target with General Antimicrobial Screening and Specific Computational Studies against SARS‐CoV‐2 Main Protease. ChemistrySelect 2024, 9. doi:10.1002/slct.202304774
- doi:10.1002/9783527817894.ch6
- Astani, E. K.; Malek Zadeh, S.; Sardari, S.; Khosravian, M. DFT QM/MM MD Calculations to Identify Intermolecular Interactions within the Active Sites of MraYAA Bound to Antibiotics Capuramycin, Carbacaprazamycin, and 3′‐Hydroxymureidomycin A. ChemistrySelect 2023, 8. doi:10.1002/slct.202302657
- Kumar, G.; Engle, K. Natural products acting against S. aureus through membrane and cell wall disruption. Natural product reports 2023, 40, 1608–1646. doi:10.1039/d2np00084a
- Manning, D.; Huang, T.-Y.; Berida, T.; Roy, S. The challenges and opportunities of developing small molecule inhibitors of MraY. Annual reports in medicinal chemistry 2023, 60, 1–27. doi:10.1016/bs.armc.2023.09.005
- Thilmont, L.; Rosinus, S.; Lutz, M.; Rohrbacher, C.; Ducho, C. Nucleoside-derived inhibitors of MraY: Medicinal chemistry with natural products. New Approaches Towards Novel Antibacterial Agents; Elsevier, 2023; pp 29–85. doi:10.1016/bs.armc.2023.09.001
- Rohrbacher, C.; Zscherp, R.; Weck, S. C.; Klahn, P.; Ducho, C. Synthesis of an Antimicrobial Enterobactin-Muraymycin Conjugate for Improved Activity Against Gram-Negative Bacteria. Chemistry (Weinheim an der Bergstrasse, Germany) 2022, 29, e202202408. doi:10.1002/chem.202202408
- Wan, H.; Ben Othman, R.; Le Corre, L.; Poinsot, M.; Oliver, M.; Amoroso, A.; Joris, B.; Touzé, T.; Auger, R.; Calvet-Vitale, S.; Bosco, M.; Gravier-Pelletier, C. New MraYAA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole. Antibiotics (Basel, Switzerland) 2022, 11, 1189. doi:10.3390/antibiotics11091189
- Singla, R. K.; Dhir, V.; Madaan, R.; Kumar, D.; Singh Bola, S.; Bansal, M.; Kumar, S.; Dubey, A. K.; Singla, S.; Shen, B. The Genus Alternanthera: Phytochemical and Ethnopharmacological Perspectives. Frontiers in pharmacology 2022, 13, 769111. doi:10.3389/fphar.2022.769111
- Arbour, C. A.; Imperiali, B. Backbone-Anchoring, Solid-Phase Synthesis Strategy To Access a Library of Peptidouridine-Containing Small Molecules. Organic letters 2022, 24, 2170–2174. doi:10.1021/acs.orglett.2c00462
- Oliver, M.; Le Corre, L.; Poinsot, M.; Bosco, M.; Wan, H.; Amoroso, A.; Joris, B.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C. A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling. Molecules (Basel, Switzerland) 2022, 27, 1769. doi:10.3390/molecules27061769
- Shao, X.; Zheng, C.; Xu, P.; Shiraishi, T.; Kuzuyama, T.; Molinaro, A.; Silipo, A.; Yu, B. Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A-94964. Angewandte Chemie (International ed. in English) 2022, 61, e202200818. doi:10.1002/anie.202200818
- Shao, X.; Zheng, C.; Xu, P.; Shiraishi, T.; Kuzuyama, T.; Molinaro, A.; Silipo, A.; Yu, B. Total Synthesis and Stereochemistry Assignment of Nucleoside Antibiotic A‐94964. Angewandte Chemie 2022, 134. doi:10.1002/ange.202200818
- Remennikov, G. Y. Synthesis of pyrimidine-containing alkaloids. The Alkaloids. Chemistry and biology 2022, 88, 49–367. doi:10.1016/bs.alkal.2021.11.001
- Guo, Z.; Tang, Y.; Tang, W.; Chen, Y. Heptose-containing bacterial natural products: structures, bioactivities, and biosyntheses. Natural product reports 2021, 38, 1887–1909. doi:10.1039/d0np00075b
- Oliver, M.; Le Corre, L.; Poinsot, M.; Corio, A.; Madegard, L.; Bosco, M.; Amoroso, A. M.; Joris, B.; Auger, R.; Touzé, T.; Bouhss, A.; Calvet-Vitale, S.; Gravier-Pelletier, C. Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors. Organic & biomolecular chemistry 2021, 19, 5844–5866. doi:10.1039/d1ob00710f
- Mitachi, K.; Mingle, D.; Kurosu, M. A Convenient Protecting Group for Uridine Ureido Nitrogen: (4,4′-Bisfluorophenyl)methoxymethyl Group. Synthesis 2021, 53, 2643–2650. doi:10.1055/a-1464-2473
- Ropponen, H.-K.; Richter, R.; Hirsch, A. K. H.; Lehr, C.-M. Mastering the Gram-Negative Bacterial Barrier - Chemical Approaches to Increase Bacterial Bioavailability of Antibiotics. Advanced drug delivery reviews 2021, 172, 339–360. doi:10.1016/j.addr.2021.02.014