Synthesis of ribavirin 2’-Me-C-nucleoside analogues

Fanny Cosson, Aline Faroux, Jean-Pierre Baltaze, Jonathan Farjon, Régis Guillot, Jacques Uziel and Nadège Lubin-Germain
Beilstein J. Org. Chem. 2017, 13, 755–761. https://doi.org/10.3762/bjoc.13.74

Supporting Information

Supporting Information File 1: Experimental details, copies of 1H NMR, 13C NMR, HRMS and X-ray spectra.
Format: PDF Size: 4.6 MB Download

Cite the Following Article

Synthesis of ribavirin 2’-Me-C-nucleoside analogues
Fanny Cosson, Aline Faroux, Jean-Pierre Baltaze, Jonathan Farjon, Régis Guillot, Jacques Uziel and Nadège Lubin-Germain
Beilstein J. Org. Chem. 2017, 13, 755–761. https://doi.org/10.3762/bjoc.13.74

How to Cite

Cosson, F.; Faroux, A.; Baltaze, J.-P.; Farjon, J.; Guillot, R.; Uziel, J.; Lubin-Germain, N. Beilstein J. Org. Chem. 2017, 13, 755–761. doi:10.3762/bjoc.13.74

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 114.4 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Micouin, L.; Piccardi, R. Organoaluminum Reagents. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering; Elsevier, 2024. doi:10.1016/b978-0-323-96025-0.00041-7
  • Nascimento, S. M. R. d.; Ferry, A.; Gallier, F.; Lubin-Germain, N.; Uziel, J.; Gonzales, S.; Miranda, L. S. d. M. E. Developments in the chemistry and biology of 1,2,3-triazolyl-C-nucleosides. Archiv der Pharmazie 2023, 357, e2300580. doi:10.1002/ardp.202300580
  • Mukherjee, D.; Hudait, N.; Sakander, N.; Kundu, S.; Rasool, B.; Sengupta, J. Synthesis of Modified C-Nucleosides of Therapeutic Significant: A Succinct Account. Synlett 2023, 35, 635–648. doi:10.1055/a-2202-8808
  • da Silva, E. F.; Antunes Fernandes, K. H.; Diedrich, D.; Gotardi, J.; Freire Franco, M. S.; Tomich de Paula da Silva, C. H.; Duarte de Souza, A. P.; Baggio Gnoatto, S. C. New triazole-substituted triterpene derivatives exhibiting anti-RSV activity: synthesis, biological evaluation, and molecular modeling. Beilstein journal of organic chemistry 2022, 18, 1524–1531. doi:10.3762/bjoc.18.161
  • Bozinovic, N.; Aguiar, V. M. d.; Ferry, A.; Gallier, F.; Lubin-Germain, N.; Uziel, J.; Miranda, L. S. d. M. E. Studies on the synthesis of 1'-CN-triazolyl-C-ribosides. Organic & biomolecular chemistry 2022, 20, 7261–7269. doi:10.1039/d2ob01403c
  • Sharma, A.; Bera, S.; Mondal, D. Advances in the synthesis of antiviral agents from carbohydrate-derived chiral pools. Journal of Carbohydrate Chemistry 2022, 41, 424–510. doi:10.1080/07328303.2023.2189473
  • Potey, L.; Dudhe, A. C.; Tumme, D.; Dudhea, R.; Sable, P. The Concept of Repurposing in COVID-19 Infection. Coronaviruses 2022, 3. doi:10.2174/2666796703666220204102622
  • Gonzalez, S.; Brzuska, G.; Ouarti, A.; Gallier, F.; Solarte, C.; Ferry, A.; Uziel, J.; Krol, E.; Lubin-Germain, N. Anti-HCV and Zika activities of ribavirin C-nucleosides analogues. Bioorganic & medicinal chemistry 2022, 68, 116858. doi:10.1016/j.bmc.2022.116858
  • Takada, H.; Takizawa, N.; Shibasaki, S.; Asaba, H.; Igarashi, M.; Shibasaki, M.; Takahashi, Y. Synthesis and antiviral activity of formycin derivatives with anti-influenza virus activity. Bioorganic & medicinal chemistry 2022, 57, 116613. doi:10.1016/j.bmc.2022.116613
  • Sabat, N.; Migianu-Griffoni, E.; Tudela, T.; Lecouvey, M.; Kellouche, S.; Carreiras, F.; Gallier, F.; Uziel, J.; Lubin-Germain, N. Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin. European journal of medicinal chemistry 2019, 188, 112009. doi:10.1016/j.ejmech.2019.112009
  • Wambecke, A.; Laurent-Issartel, C.; Leroy-Dudal, J.; Giffard, F.; Cosson, F.; Lubin-Germain, N.; Uziel, J.; Kellouche, S.; Carreiras, F. Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells. PloS one 2019, 14, e0225860. doi:10.1371/journal.pone.0225860
Other Beilstein-Institut Open Science Activities