Design and biological characterization of novel cell-penetrating peptides preferentially targeting cell nuclei and subnuclear regions

Scholarly Works

• Mai, L. D.; Wimberley, S. C.; Champion, J. A. Intracellular delivery strategies using membrane-interacting peptides and proteins. Nanoscale 2024, 16, 15465–15480. doi:10.1039/d4nr02093f
• Al Musaimi, O. Peptide Therapeutics: Unveiling the Potential against Cancer-A Journey through 1989. Cancers 2024, 16, 1032. doi:10.3390/cancers16051032
• Saraswat, S.; Chugh, A. Engraulisin: A novel marine derived cell penetrating peptide with activity against drug resistant bacteria. Biochimica et biophysica acta. Biomembranes 2023, 1866, 184255. doi:10.1016/j.bbamem.2023.184255
• Langel, Ü. Targeting Specific Barriers. CPP, Cell-Penetrating Peptides; Springer International Publishing, 2023; pp 219–262. doi:10.1007/978-3-031-38731-9_9
• Stillger, K.; Neundorf, I. Cell-permeable peptide-based delivery vehicles useful for subcellular targeting and beyond. Cellular signalling 2023, 109, 110796. doi:10.1016/j.cellsig.2023.110796
• Asrorov, A. M.; Wang, H.; Zhang, M.; Wang, Y.; He, Y.; Sharipov, M.; Yili, A.; Huang, Y. Cell penetrating peptides: Highlighting points in cancer therapy. Drug development research 2023, 84, 1037–1071. doi:10.1002/ddr.22076
• Mukherjee, A. G.; Wanjari, U. R.; Gopalakrishnan, A. V.; Bradu, P.; Biswas, A.; Ganesan, R.; Renu, K.; Dey, A.; Vellingiri, B.; El Allali, A.; Alsamman, A. M.; Zayed, H.; George Priya Doss, C. Evolving strategies and application of proteins and peptide therapeutics in cancer treatment. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023, 163, 114832. doi:10.1016/j.biopha.2023.114832
• Urandur, S.; Sullivan, M. O. Peptide-Based Vectors: A Biomolecular Engineering Strategy for Gene Delivery. Annual review of chemical and biomolecular engineering 2023, 14, 243–264. doi:10.1146/annurev-chembioeng-101121-070232
• Zeng, Z.; Li, C.; Zhu, Y.; Yang, L.; Shi, S.; Yang, F.; Feng, X. Dibenzocyclooctyne linked lysine-cyclodextrin for efficient intranucleus delivery of proteins. Journal of controlled release : official journal of the Controlled Release Society 2022, 352, 759–765. doi:10.1016/j.jconrel.2022.11.001
• Grabeck, J.; Lützenburg, T.; Frommelt, P.; Neundorf, I. Comparing Variants of the Cell-Penetrating Peptide sC18 to Design Peptide-Drug Conjugates. Molecules (Basel, Switzerland) 2022, 27, 6656. doi:10.3390/molecules27196656
• Alkhashrom, S.; Kicuntod, J.; Stillger, K.; Lützenburg, T.; Anzenhofer, C.; Neundorf, I.; Marschall, M.; Eichler, J. A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex. Pharmaceuticals (Basel, Switzerland) 2022, 15, 1040. doi:10.3390/ph15091040
• Lin, J.; Yang, K.; New, E. J. doi:10.1002/9781119749844.ch3
• Fu, C.; Yu, L.; Miao, Y.; Liu, X.; Yu, Z.; Wei, M. Peptide-drug conjugates (PDCs): a novel trend of research and development on targeted therapy, hype or hope?. Acta pharmaceutica Sinica. B 2022, 13, 498–516. doi:10.1016/j.apsb.2022.07.020
• Kuznik, N. C.; Solozobova, V.; Lee, I. I.; Jung, N.; Yang, L.; Nienhaus, K.; Ntim, E. A.; Rottenberg, J. T.; Muhle-Goll, C.; Kumar, A. R.; Peravali, R.; Gräßle, S.; Gourain, V.; Deville, C.; Cato, L.; Neeb, A.; Dilger, M.; Cramer von Clausbruch, C. A.; Weiss, C.; Kieffer, B.; Nienhaus, G. U.; Brown, M.; Bräse, S.; Cato, A. C. B. A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway. iScience 2022, 25, 104175. doi:10.1016/j.isci.2022.104175
• Cerrato, C. P.; Langel, Ü. An update on cell-penetrating peptides with intracellular organelle targeting. Expert opinion on drug delivery 2022, 19, 133–146. doi:10.1080/17425247.2022.2034784
• Gessner, I.; Klimpel, A.; Neundorf, I. Synthesis of Cell-Penetrating Peptide Coated Silica Nanoparticles and Their Physicochemical and Biological Characterization. Methods in molecular biology (Clifton, N.J.) 2021, 2383, 105–117. doi:10.1007/978-1-0716-1752-6_7
• Lin, J.; Yang, K.; New, E. J. Strategies for organelle targeting of fluorescent probes. Organic & biomolecular chemistry 2021, 19, 9339–9357. doi:10.1039/d1ob01447a
• Kim, G. C.; Cheon, D. H.; Lee, Y. Challenge to overcome current limitations of cell-penetrating peptides. Biochimica et biophysica acta. Proteins and proteomics 2021, 1869, 140604. doi:10.1016/j.bbapap.2021.140604
• Khan, M. M.; Filipczak, N.; Torchilin, V. P. Cell penetrating peptides: A versatile vector for co-delivery of drug and genes in cancer. Journal of controlled release : official journal of the Controlled Release Society 2020, 330, 1220–1228. doi:10.1016/j.jconrel.2020.11.028
• Díaz-Gómez, J. L.; Neundorf, I.; López-Castillo, L.-M.; Castorena-Torres, F.; Serna-Saldívar, S. O.; García-Lara, S. In Silico Analysis and In Vitro Characterization of the Bioactive Profile of Three Novel Peptides Identified from 19 kDa α-Zein Sequences of Maize. Molecules (Basel, Switzerland) 2020, 25, 5405. doi:10.3390/molecules25225405

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