Supporting Information
| Supporting Information File 1: Experimental procedures and analytical data. | ||
| Format: PDF | Size: 286.6 KB | Download |
| Supporting Information File 2: Copies of 1H and 13C NMR spectra of all prepared compounds. | ||
| Format: PDF | Size: 4.9 MB | Download |
Cite the Following Article
Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases
Maroš Bella, Sergej Šesták, Ján Moncoľ, Miroslav Koóš and Monika Poláková
Beilstein J. Org. Chem. 2018, 14, 2156–2162.
https://doi.org/10.3762/bjoc.14.189
How to Cite
Bella, M.; Šesták, S.; Moncoľ, J.; Koóš, M.; Poláková, M. Beilstein J. Org. Chem. 2018, 14, 2156–2162. doi:10.3762/bjoc.14.189
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 132.0 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Kalník, M.; Šesták, S.; Kóňa, J.; Bella, M.; Poláková, M. Synthesis, α-mannosidase inhibition studies and molecular modeling of 1,4-imino-ᴅ-lyxitols and their C-5-altered N-arylalkyl derivatives. Beilstein journal of organic chemistry 2023, 19, 282–293. doi:10.3762/bjoc.19.24
- Kóňa, J.; Šesták, S.; Wilson, I. B. H.; Poláková, M. 1,4-Dideoxy-1,4-imino-D- and L-lyxitol-based inhibitors bind to Golgi α-mannosidase II in different protonation forms. Organic & biomolecular chemistry 2022, 20, 8932–8943. doi:10.1039/d2ob01545e
- Kalník, M.; Zajičková, M.; Kóňa, J.; Šesták, S.; Moncoľ, J.; Koóš, M.; Bella, M. Synthesis of hydroxymethyl analogues of mannostatin A and their evaluation as inhibitors of GH38 α-mannosidases. New Journal of Chemistry 2021, 45, 13539–13548. doi:10.1039/d1nj02351a
- Lee, Z. Y.; Loo, J. S. E.; Wibowo, A.; Mohammat, M. F.; Foo, J. B. Targeting cancer via Golgi α-mannosidase II inhibition: How far have we come in developing effective inhibitors?. Carbohydrate research 2021, 508, 108395. doi:10.1016/j.carres.2021.108395
- Klunda, T.; Hricovíni, M.; Šesták, S.; Kóňa, J.; Poláková, M. Selective Golgi α-mannosidase II inhibitors: N-alkyl substituted pyrrolidines with a basic functional group. New Journal of Chemistry 2021, 45, 10940–10951. doi:10.1039/d1nj01176f
- Rísquez-Cuadro, R.; Matsumoto, R.; Ortega-Caballero, F.; Nanba, E.; Higaki, K.; Fernández, J. M. G.; Mellet, C. O. Pharmacological Chaperones for the Treatment of α-Mannosidosis. Journal of medicinal chemistry 2019, 62, 5832–5843. doi:10.1021/acs.jmedchem.9b00153
