Nucleoside macrocycles formed by intramolecular click reaction: efficient cyclization of pyrimidine nucleosides decorated with 5'-azido residues and 5-octadiynyl side chains

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• Ji, D.; Zhang, K.; Yarshova, M.; Kwok, C. K. L-RNA Aptamer-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Application. Accounts of chemical research 2025, 58, 3247–3258. doi:10.1021/acs.accounts.5c00468
• Tiwari, V. K.; Jaiswal, M. K.; Rajkhowa, S.; Singh, S. K. Intramolecular Click Chemistry in Organic Synthesis. Materials Horizons: From Nature to Nanomaterials; Springer Nature Singapore, 2024; pp 559–601. doi:10.1007/978-981-97-4596-8_17
• Tiwari, V. K.; Jaiswal, M. K.; Rajkhowa, S.; Singh, S. K. Click Chemistry in Nucleic Acids. Materials Horizons: From Nature to Nanomaterials; Springer Nature Singapore, 2024; pp 437–478. doi:10.1007/978-981-97-4596-8_14
• Chen, A.; Wang, G. Synthesis of carbohydrate-containing macrocycles. Synthetic Strategies in Carbohydrate Chemistry; Elsevier, 2024; pp 407–522. doi:10.1016/b978-0-323-91729-2.00012-4
• Luzzio, F. A. Diversity of heterocyclic reactants in the click reaction. Advances in Heterocyclic Chemistry; Elsevier, 2024; pp 95–176. doi:10.1016/bs.aihch.2023.11.002
• Burchiellaro, K.; Mieczkowski, A. Synthesis and applications of cyclonucleosides: an update (2010-2023). Molecular diversity 2023, 28, 3427–3443. doi:10.1007/s11030-023-10740-5
• Kanagawa, T.; Tachibana, S.; Masaki, Y.; Seio, K. Synthesis and Conformational Analyses of Cyclonucleoside Having 13-Membered Ring Bridging Nucleobase and 5'-Position via a Linker Containing Sulfonamide. Organic letters 2023, 25, 7868–7872. doi:10.1021/acs.orglett.3c03094
• Jaiswal, M. K.; Tiwari, V. K. Growing Impact of Intramolecular Click Chemistry in Organic Synthesis. Chemical record (New York, N.Y.) 2023, 23, e202300167. doi:10.1002/tcr.202300167
• Clément, D. A.; Gelin, M.; Leseigneur, C.; Huteau, V.; Mondange, L.; Pons, J.-L.; Dussurget, O.; Lionne, C.; Labesse, G.; Pochet, S. Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria. European journal of medicinal chemistry 2022, 246, 114941. doi:10.1016/j.ejmech.2022.114941
• Cicetti, S.; Maestre, E.; Spanevello, R. A.; Sarotti, A. M. Towards the Synthesis of Highly Hindered Pyrrolidines by Intramolecular AAC Click Reactions: What Can Be Learned from DFT Calculations?**. European Journal of Organic Chemistry 2022, 2022. doi:10.1002/ejoc.202200478
• Kawamura, S.; Palte, R. L.; Kim, H.-Y.; Saurí, J.; Sondey, C.; Mansueto, M. S.; Altman, M. D.; Machacek, M. R. Design and synthesis of unprecedented 9- and 10-membered cyclonucleosides with PRMT5 inhibitory activity. Bioorganic & medicinal chemistry 2022, 66, 116820. doi:10.1016/j.bmc.2022.116820
• Kareem, N. S.; Mohammed, S. A.; Abed, M. J.; Aneed, A. H.; Kamal, H. M.; Zahid, N. I.; Sabah, K. J. New macrocycles incorporating glycolipids via copper-catalyzed triazole coupling. Journal of Carbohydrate Chemistry 2022, 41, 1–17. doi:10.1080/07328303.2022.2039685
• Ji, D.; Lyu, K.; Zhao, H.; Kwok, C. K. Circular L-RNA aptamer promotes target recognition and controls gene activity. Nucleic acids research 2021, 49, 7280–7291. doi:10.1093/nar/gkab593
• Agrahari, A. K.; Bose, P.; Jaiswal, M. K.; Rajkhowa, S.; Singh, A. S.; Hotha, S.; Mishra, N.; Tiwari, V. K. Cu(I)-Catalyzed Click Chemistry in Glycoscience and Their Diverse Applications. Chemical reviews 2021, 121, 7638–7956. doi:10.1021/acs.chemrev.0c00920
• Hameed, A.; Hameed, A.; Raza, A.; Farooq, T. Advances in Triazole Chemistry - Site-specific Incorporation of Triazole for Functionalization of Nucleotides, Oligonucleotides, and Nucleic Acids. Advances in Triazole Chemistry; Elsevier, 2021; pp 49–75. doi:10.1016/b978-0-12-817113-4.00006-8
• Prasher, P.; Sharma, M. Tailored therapeutics based on 1,2,3-1H-triazoles: a mini review. MedChemComm 2019, 10, 1302–1328. doi:10.1039/c9md00218a

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