Supporting Information
| Supporting Information File 1: Experimental details, characterization data and copies of NMR spectra. | ||
| Format: PDF | Size: 1.0 MB | Download |
Cite the Following Article
Synthesis of 3-aminocoumarin-N-benzylpyridinium conjugates with nanomolar inhibitory activity against acetylcholinesterase
Nisachon Khunnawutmanotham, Cherdchai Laongthipparos, Patchreenart Saparpakorn, Nitirat Chimnoi and Supanna Techasakul
Beilstein J. Org. Chem. 2018, 14, 2545–2552.
https://doi.org/10.3762/bjoc.14.231
How to Cite
Khunnawutmanotham, N.; Laongthipparos, C.; Saparpakorn, P.; Chimnoi, N.; Techasakul, S. Beilstein J. Org. Chem. 2018, 14, 2545–2552. doi:10.3762/bjoc.14.231
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 393.1 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Polo-Cuadrado, E.; Rojas-Peña, C.; Acosta-Quiroga, K.; Camargo-Ayala, L.; Rodríguez-Núñez, Y. A.; Osorio, E.; López, J. J.; Brid-Cuadrado, R.; Gutierrez, M. Exploring pyridinium-based inhibitors of cholinesterases: A review of synthesis, efficacy, and structural insights. European Journal of Medicinal Chemistry Reports 2025, 14, 100270. doi:10.1016/j.ejmcr.2025.100270
- Hannongbua, S.; Saparpakorn, P. Rational Structure-Based Drug Design. Encyclopedia of Bioinformatics and Computational Biology; Elsevier, 2025; pp 655–668. doi:10.1016/b978-0-323-95502-7.00208-6
- Mohan, R. D.; Kulkarni, N. V. Recent developments in the design of functional derivatives of edaravone and exploration of their antioxidant activities. Molecular diversity 2024, 29, 1895–1910. doi:10.1007/s11030-024-10940-7
- Khunnawutmanotham, N.; Sooknual, P.; Batsomboon, P.; Ploypradith, P.; Chimnoi, N.; Patigo, A.; Saparpakorn, P.; Techasakul, S. Synthesis, Antiacetylcholinesterase Activity, and Molecular Dynamics Simulation of Aporphine-benzylpyridinium Conjugates. ACS medicinal chemistry letters 2023, 15, 132–142. doi:10.1021/acsmedchemlett.3c00467
- Vignaux, P. A.; Lane, T. R.; Urbina, F.; Gerlach, J.; Puhl, A. C.; Snyder, S. H.; Ekins, S. Validation of Acetylcholinesterase Inhibition Machine Learning Models for Multiple Species. Chemical research in toxicology 2023, 36, 188–201. doi:10.1021/acs.chemrestox.2c00283
- Patra, P.; Manna, S.; Patra, S.; Samanta, K. The synthesis, biological evaluation, and fluorescence study of 3-aminocoumarin and their derivatives: a brief review. Monatshefte für Chemie - Chemical Monthly 2023, 154, 1–31. doi:10.1007/s00706-022-03010-x
- Sepehri, S.; Saeedi, M.; Larijani, B.; Mahdavi, M. Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer's disease. Frontiers in chemistry 2022, 10, 936240. doi:10.3389/fchem.2022.936240
- Krajňáková, J.; Joniak, J.; Putala, M.; Górová, R.; Jurdáková, H.; Stankovičová, H. Mild and highly efficient deacetylation of acetamido and acetoxy coumarins: A convenient and expeditious synthesis of substituted 3-aminocoumarins. Synthetic Communications 2021, 51, 3277–3291. doi:10.1080/00397911.2021.1968904
- Gupta, M.; Ojha, M.; Yadav, D.; Pant, S.; Yadav, R. Novel Benzylated (Pyrrolidin-2-one)/(Imidazolidin-2-one) Derivatives as Potential Anti-Alzheimer's Agents: Synthesis and Pharmacological Investigations. ACS chemical neuroscience 2020, 11, 2849–2860. doi:10.1021/acschemneuro.0c00403
- Mahajan, S.; Slathia, N.; Kapoor, K. K. Beckmann rearrangement: Thiamine hydrochloride as a remarkable catalyst for one-pot synthesis of amides from ketones. Tetrahedron Letters 2020, 61, 151859. doi:10.1016/j.tetlet.2020.151859
