Mechanochemistry of nucleosides, nucleotides and related materials

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• Speight, I. R.; Mack, J. Moving mechanochemistry forward: accelerating and tuning organic synthesis by mechanochemistry. RSC Mechanochemistry 2026, 3, 9–14. doi:10.1039/d5mr90035b
• Xu, Q.; Cui, Q.; Wang, J. Efficient synthesis of benzo(hetero)aryl-5-yl(2-hydroxyphenyl)methanones via mechanochemical benzannulation. Chemical communications (Cambridge, England) 2025. doi:10.1039/d5cc06020f
• Mele, F.; Biedermann, N.; Suster, C.; Templ, J.; Stanetty, C.; Schnürch, M. Mechanochemistry Enables Rapid and Solvent-Free Wittig Reactions on Sugars. ChemSusChem 2025, 19, e202502026. doi:10.1002/cssc.202502026
• Nagao, A.; Kubota, K.; Ito, H. All-step Mechanochemical Approach for the Rapid and Solventless Synthesis of Boscalid. Synthesis 2025. doi:10.1055/a-2744-6831
• Tomita, N.; Sajiki, H.; Ikawa, T. Synthesis of cyclic carbonates via silver-catalysed fixation of CO 2 to propargyl alcohols under mechanochemical conditions. RSC Mechanochemistry 2025, 2, 809–812. doi:10.1039/d5mr00072f
• Jana, K.; Kubota, K.; Ito, H. A mechanochemical [2+2+2] cycloaddition facilitated by a cobalt(ii) catalyst and piezoelectric materials. Chemical science 2025, 16, 11468–11474. doi:10.1039/d5sc02074c
• Méndez-Gálvez, C.; Barnå, F.; Olsthoorn, B.; Estébanez Rosich, D.; Gates, P. J.; Pilarski, L. T. Solventless Catalytic C-H and C-X Functionalization without Ball Milling. The Journal of organic chemistry 2025, 90, 8846–8856. doi:10.1021/acs.joc.5c00109
• Yamamoto, T.; Kubota, K.; Harabuchi, Y.; Ito, H. Scaling theory for the kinetics of mechanochemical reactions with convective flow. RSC Mechanochemistry 2025, 2, 230–239. doi:10.1039/d4mr00091a
• Kubota, K.; Makino, T.; Kondo, K.; Seo, T.; Jin, M.; Ito, H. Solid-state aromatic nucleophilic fluorination: a rapid, practical, and environmentally friendly route to N-heteroaryl fluorides. Green Chemistry 2025, 27, 1771–1776. doi:10.1039/d4gc06362g
• Kudalkar, M. V.; Patel, M. A.; Sanghvi, Y. S.; Kapdi, A. R. Achieving Sustainability in the Assembly of Modified Nucleosides Using Green Solvents. Sustainability & Circularity NOW 2024, 2. doi:10.1055/a-2479-0995
• Kubota, K.; Kawamura, S.; Jiang, J.; Maeda, S.; Ito, H. Mechanochemical generation of aryl barium nucleophiles from unactivated barium metal. Chemical science 2024, 15, 17453–17459. doi:10.1039/d4sc05361c
• Kubota, K.; Hisazumi, R.; Seo, T.; Ito, H. Mechanochemistry enabled highly efficient solvent-free deoxygenation of phosphine oxides in air. RSC Mechanochemistry 2024, 1, 250–254. doi:10.1039/d4mr00011k
• Seo, T. Dual Nickel(II)/Mechanoredox Catalysis: Mechanical-Force-Driven Aryl-Amination Reactions Using Ball Milling and Piezoelectric Materials. Springer Theses; Springer Nature Singapore, 2024; pp 243–278. doi:10.1007/978-981-97-1991-4_8
• Seo, T. Mechanochemistry-Directed Ligand Design: Development of a High-Performance Phosphine Ligand for Palladium-Catalyzed Mechanochemical Organoboron Cross-Coupling. Springer Theses; Springer Nature Singapore, 2024; pp 161–210. doi:10.1007/978-981-97-1991-4_6
• Seo, T. Tackling Solubility Issues in Organic Synthesis: Solid-State Cross-Coupling of Insoluble Aryl Halides. Springer Theses; Springer Nature Singapore, 2024; pp 93–142. doi:10.1007/978-981-97-1991-4_4
• Yamamoto, T.; Kubota, K.; Ito, H. Dissolution-Limited Reactions in Solid-State Synthesis. Nihon Reoroji Gakkaishi 2024, 52, 161–170. doi:10.1678/rheology.52.161
• Kondo, K.; Kubota, K.; Ito, H. Mechanochemistry enabling highly efficient Birch reduction using sodium lumps and d-(+)-glucose. Chemical science 2024, 15, 4452–4457. doi:10.1039/d3sc06052g
• Navarro, V.; Vasco, F.; Bantreil, X.; Lamaty, F.; Peyrottes, S.; Roy, B. Ball‐Milling to Access Dinucleoside Polyphosphates and Analogues. Advanced Synthesis & Catalysis 2024, 366, 1776–1781. doi:10.1002/adsc.202400057
• Seo, T.; Kubota, K.; Ito, H. Dual Nickel(II)/Mechanoredox Catalysis: Mechanical‐Force‐Driven Aryl‐Amination Reactions Using Ball Milling and Piezoelectric Materials. Angewandte Chemie 2023, 135. doi:10.1002/ange.202311531
• Seo, T.; Kubota, K.; Ito, H. Dual Nickel(II)/Mechanoredox Catalysis: Mechanical-Force-Driven Aryl-Amination Reactions Using Ball Milling and Piezoelectric Materials. Angewandte Chemie (International ed. in English) 2023, 62, e202311531. doi:10.1002/anie.202311531

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