Supporting Information
Supporting Information File 1: Complete experimental procedures and characterization data. | ||
Format: PDF | Size: 419.1 KB | Download |
Cite the Following Article
Synthesis of a tubugi-1-toxin conjugate by a modulizable disulfide linker system with a neuropeptide Y analogue showing selectivity for hY1R-overexpressing tumor cells
Rainer Kufka, Robert Rennert, Goran N. Kaluđerović, Lutz Weber, Wolfgang Richter and Ludger A. Wessjohann
Beilstein J. Org. Chem. 2019, 15, 96–105.
https://doi.org/10.3762/bjoc.15.11
How to Cite
Kufka, R.; Rennert, R.; Kaluđerović, G. N.; Weber, L.; Richter, W.; Wessjohann, L. A. Beilstein J. Org. Chem. 2019, 15, 96–105. doi:10.3762/bjoc.15.11
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
Picture with graphical abstract, title and authors for social media postings and presentations. | ||
Format: PNG | Size: 951.4 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Eldehna, W. M.; Fares, M.; Bonardi, A.; Avgenikos, M.; Baselious, F.; Schmidt, M.; Al-Warhi, T.; Abdel-Aziz, H. A.; Rennert, R.; Peat, T. S.; Supuran, C. T.; Wessjohann, L. A.; Ibrahim, H. S. 4-(Pyrazolyl)benzenesulfonamide Ureas as Carbonic Anhydrases Inhibitors and Hypoxia-Mediated Chemo-Sensitizing Agents in Colorectal Cancer Cells. Journal of medicinal chemistry 2024. doi:10.1021/acs.jmedchem.4c01894
- Llanes, D.; Rennert, R.; Jänicke, P.; Morgan, I.; Reguera, L.; Rivera, D. G.; Ricardo, M. G.; Wessjohann, L. A. Development of bombesin-tubulysin conjugates using multicomponent chemistry to functionalize both the payload and the homing peptide. Frontiers in Pharmacology 2024, 15. doi:10.3389/fphar.2024.1408091
- Ricardo, M. G.; Llanes, D.; Rennert, R.; Jänicke, P.; Rivera, D. G.; Wessjohann, L. A. Improved Access to Potent Anticancer Tubulysins and Linker-Functionalized Payloads Via an All-On-Resin Strategy. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 30, e202401943. doi:10.1002/chem.202401943
- Lam, Y. T. H.; Hoppe, J.; Dang, Q. N.; Porzel, A.; Soboleva, A.; Brandt, W.; Rennert, R.; Hussain, H.; Davari, M. D.; Wessjohann, L.; Arnold, N. Purpurascenines A-C, Azepino-Indole Alkaloids from Cortinarius purpurascens: Isolation, Biosynthesis, and Activity Studies on the 5-HT2A Receptor. Journal of natural products 2023, 86, 1373–1384. doi:10.1021/acs.jnatprod.2c00716
- Sánchez, M. L.; Rodríguez, F. D.; Coveñas, R. Neuropeptide Y Peptide Family and Cancer: Antitumor Therapeutic Strategies. International journal of molecular sciences 2023, 24, 9962. doi:10.3390/ijms24129962
- Xiangrong, X.; Yao, L.; Yao, A. The Recent Developments of ADCs with the Tubulysins as the Payloads. Mini reviews in medicinal chemistry 2023, 23, 1797–1805. doi:10.2174/1389557523666230220121648
- Fu, C.; Yu, L.; Miao, Y.; Liu, X.; Yu, Z.; Wei, M. Peptide-drug conjugates (PDCs): a novel trend of research and development on targeted therapy, hype or hope?. Acta pharmaceutica Sinica. B 2022, 13, 498–516. doi:10.1016/j.apsb.2022.07.020
- Rodríguez-Mejía, L. C.; Romero-Estudillo, I.; Rivillas-Acevedo, L. A.; French-Pacheco, L.; Silva-Martínez, G. A.; Alvarado-Caudillo, Y.; Colín-Castelán, D.; Rodríguez-Ríos, D.; Wrobel, K.; Wrobel, K.; Lund, G.; Zaina, S. The DNA Methyltransferase Inhibitor RG108 is Converted to Activator Following Conjugation with Short Peptides. International Journal of Peptide Research and Therapeutics 2022, 28. doi:10.1007/s10989-022-10390-5
- Dube, M.; Saoud, M.; Rennert, R.; Fotso, G. W.; Andrae-Marobela, K.; Imming, P.; Häberli, C.; Keiser, J.; Arnold, N. Anthelmintic Activity and Cytotoxic Effects of Compounds Isolated from the Fruits of Ozoroa insignis Del. (Anacardiaceae). Biomolecules 2021, 11, 1893. doi:10.3390/biom11121893
- Lin, S.-T.; Li, Y.-Z.; Sun, X.-Q.; Chen, Q.-Q.; Huang, S.-F.; Lin, S.; Cai, S.-Q. Update on the Role of Neuropeptide Y and Other Related Factors in Breast Cancer and Osteoporosis. Frontiers in endocrinology 2021, 12, 705499. doi:10.3389/fendo.2021.705499
- Newman, D. J. doi:10.1002/0471266949.bmc119.pub2
- Rongjun, H.; Jia, P.; John, P. M.; Fa, L. The Chemical Methods of Disulfide Bond Formation and Their Applications to Drug Conjugates. Current Organic Chemistry 2020, 23, 2802–2821. doi:10.2174/1385272823666191202111723
- Kienast, C.; Gunga, H.-C.; Steinach, M. Neuropeptide Y – Its role in human performance and extreme environments. REACH 2019, 14-15, 100032. doi:10.1016/j.reach.2019.100032