Cite the Following Article
Current understanding and biotechnological application of the bacterial diterpene synthase CotB2
Ronja Driller, Daniel Garbe, Norbert Mehlmer, Monika Fuchs, Keren Raz, Dan Thomas Major, Thomas Brück and Bernhard Loll
Beilstein J. Org. Chem. 2019, 15, 2355–2368.
https://doi.org/10.3762/bjoc.15.228
How to Cite
Driller, R.; Garbe, D.; Mehlmer, N.; Fuchs, M.; Raz, K.; Major, D. T.; Brück, T.; Loll, B. Beilstein J. Org. Chem. 2019, 15, 2355–2368. doi:10.3762/bjoc.15.228
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
Picture with graphical abstract, title and authors for social media postings and presentations. | ||
Format: PNG | Size: 415.2 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Schwartz, R.; Zev, S.; Major, D. T. Mechanistic docking in terpene synthases using EnzyDock. Methods in enzymology 2024, 699, 265–292. doi:10.1016/bs.mie.2024.04.005
- Alsup, T. A.; Opoku, M. O.; Rudolf, J. D. Characterization of UbiA terpene synthases with a precursor overproduction system in Escherichia coli. Methods in enzymology 2024, 699, 395–417. doi:10.1016/bs.mie.2024.02.001
- Spencer, T. A.; Ditchfield, R. Tryptophan Stabilization of a Biochemical Carbocation Evaluated by Analysis of π Complexes of 3-Ethylindole with the t-Butyl Cation. ACS omega 2023, 8, 26497–26507. doi:10.1021/acsomega.3c03259
- Tarasova, E. V.; Luchnikova, N. A.; Grishko, V. V.; Ivshina, I. B. Actinomycetes as Producers of Biologically Active Terpenoids: Current Trends and Patents. Pharmaceuticals (Basel, Switzerland) 2023, 16, 872. doi:10.3390/ph16060872
- Li, Z.; Rudolf, J. D. Biosynthesis, enzymology, and future of eunicellane diterpenoids. Journal of industrial microbiology & biotechnology 2023, 50. doi:10.1093/jimb/kuad027
- Xu, B.; Ning, W.; Wei, X.; Rudolf, J. D. Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability. Organic & biomolecular chemistry 2022, 20, 8833–8837. doi:10.1039/d2ob01931k
- Gong, K.; Yong, D.; Fu, J.; Li, A.; Zhang, Y.; Li, R. Diterpenoids from Streptomyces: Structures, Biosyntheses and Bioactivities. Chembiochem : a European journal of chemical biology 2022, 23, e202200231. doi:10.1002/cbic.202200231
- Ringel, M.; Dimos, N.; Himpich, S.; Haack, M.; Huber, C.; Eisenreich, W.; Schenk, G.; Loll, B.; Brück, T. Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol. Microbial cell factories 2022, 21, 64. doi:10.1186/s12934-022-01791-8
- Huang, Z.-Y.; Ye, R.-Y.; Yu, H.-L.; Li, A.; Xu, J.-H. Mining methods and typical structural mechanisms of terpene cyclases. Bioresources and bioprocessing 2021, 8, 1–27. doi:10.1186/s40643-021-00421-2
- Zhu, C.; Xu, B.; Adpressa, D. A.; Rudolf, J. D.; Loesgen, S. Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid. Angewandte Chemie (International ed. in English) 2021, 60, 14163–14170. doi:10.1002/anie.202102453
- Zhu, C.; Xu, B.; Adpressa, D. A.; Rudolf, J. D.; Loesgen, S. Entdeckung und Biosynthese eines strukturdynamischen antibakteriellen Diterpenoids. Angewandte Chemie 2021, 133, 14282–14289. doi:10.1002/ange.202102453
- Xu, B.; Li, Z.; Alsup, T. A.; Ehrenberger, M. A.; Rudolf, J. D. Bacterial diterpene synthases prenylate small molecules. ACS catalysis 2021, 11, 5906–5915. doi:10.1021/acscatal.1c01113
- Raz, K.; Driller, R.; Dimos, N.; Ringel, M.; Brück, T.; Loll, B.; Major, D. T. The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. Journal of the American Chemical Society 2020, 142, 21562–21574. doi:10.1021/jacs.0c11348
- Tang, X.; Zhang, F.; Zeng, T.; Li, W.; Yin, S.; Wu, R. Enzymatic Plasticity Inspired by the Diterpene Cyclase CotB2. ACS chemical biology 2020, 15, 2820–2832. doi:10.1021/acschembio.0c00645
- Ringel, M.; Reinbold, M.; Hirte, M.; Haack, M.; Huber, C.; Eisenreich, W.; Masri, M.; Schenk, G.; Guddat, L. W.; Loll, B.; Kerr, R. G.; Garbe, D.; Brück, T. Towards a sustainable generation of pseudopterosin-type bioactives. Green Chemistry 2020, 22, 6033–6046. doi:10.1039/d0gc01697g
- Raz, K.; Levi, S.; Gupta, P. K.; Major, D. T. Enzymatic control of product distribution in terpene synthases: insights from multiscale simulations. Current opinion in biotechnology 2020, 65, 248–258. doi:10.1016/j.copbio.2020.06.002
- Liu, Y.; Duan, A.; Chen, L.; Wang, D.; Xie, Q.; Xiang, B.; Lin, Y.; Hao, X.; Zhu, X. A Fungal Diterpene Synthase Is Responsible for Sterol Biosynthesis for Growth. Frontiers in microbiology 2020, 11, 1426. doi:10.3389/fmicb.2020.01426