One-pot synthesis of substituted pyrrolo[3,4-b]pyridine-4,5-diones based on the reaction of N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamide with amines

Valeriya G. Melekhina, Andrey N. Komogortsev, Boris V. Lichitsky, Vitaly S. Mityanov, Artem N. Fakhrutdinov, Arkady A. Dudinov, Vasily A. Migulin, Yulia V. Nelyubina, Elizaveta K. Melnikova and Michail M. Krayushkin
Beilstein J. Org. Chem. 2019, 15, 2840–2846. https://doi.org/10.3762/bjoc.15.277

Supporting Information

Supporting Information File 1: Experimental procedures, characterization data of all products, copies of 1H, 13C, 2D NMR, and HRMS spectra of all compounds, and X-ray data for compound 1e.
Format: PDF Size: 4.5 MB Download

Cite the Following Article

One-pot synthesis of substituted pyrrolo[3,4-b]pyridine-4,5-diones based on the reaction of N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamide with amines
Valeriya G. Melekhina, Andrey N. Komogortsev, Boris V. Lichitsky, Vitaly S. Mityanov, Artem N. Fakhrutdinov, Arkady A. Dudinov, Vasily A. Migulin, Yulia V. Nelyubina, Elizaveta K. Melnikova and Michail M. Krayushkin
Beilstein J. Org. Chem. 2019, 15, 2840–2846. https://doi.org/10.3762/bjoc.15.277

How to Cite

Melekhina, V. G.; Komogortsev, A. N.; Lichitsky, B. V.; Mityanov, V. S.; Fakhrutdinov, A. N.; Dudinov, A. A.; Migulin, V. A.; Nelyubina, Y. V.; Melnikova, E. K.; Krayushkin, M. M. Beilstein J. Org. Chem. 2019, 15, 2840–2846. doi:10.3762/bjoc.15.277

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 181.2 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Durham, A. C.; Liu, C. R.; Wang, Y.-M. Iron-Mediated C-H Functionalization of Unactivated Alkynes for the Synthesis of Derivatized Dihydropyrrolones: Regioselectivity Under Thermodynamic Control. Chemistry (Weinheim an der Bergstrasse, Germany) 2023, 29, e202301195. doi:10.1002/chem.202301195
  • Milyutin, C. V.; Komogortsev, A. N.; Lichitsky, B. V.; Minyaev, M. E.; Melekhina, V. G. Synthesis of substituted 8H-benzo[h]pyrano[2,3-f]quinazolin-8-ones via photochemical 6π-electrocyclization of pyrimidines containing an allomaltol fragment. Beilstein journal of organic chemistry 2023, 19, 778–788. doi:10.3762/bjoc.19.58
  • Milyutin, C. V.; Komogortsev, A. N.; Lichitsky, B. V.; Melekhina, V. G. A study of the photochemical behavior of terarylenes containing allomaltol and pyrazole fragments. Beilstein journal of organic chemistry 2022, 18, 588–596. doi:10.3762/bjoc.18.61
  • Del Corte, X.; López-Francés, A.; Villate-Beitia, I.; Sainz-Ramos, M.; Martínez de Marigorta, E.; Palacios, F.; Alonso, C.; de Los Santos, J. M.; Pedraz, J. L.; Vicario, J. Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group. Pharmaceuticals (Basel, Switzerland) 2022, 15, 511. doi:10.3390/ph15050511
  • del Corte, X.; López-Francés, A.; Maestro, A.; Villate-Beitia, I.; Sainz-Ramos, M.; de Marigorta, E. M.; Pedraz, J. L.; Palacios, F.; Vicario, J. A Multicomponent Protocol for the Synthesis of Highly Functionalized γ-Lactam Derivatives and Their Applications as Antiproliferative Agents. Pharmaceuticals (Basel, Switzerland) 2021, 14, 782. doi:10.3390/ph14080782
Other Beilstein-Institut Open Science Activities