Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering

Scholarly Works

• Struwe, H.; Nguyen, T.; Schwörer, S.; Droste, J.; Spinck, H.; Kirschning, A. Chemoenzymatic Formation of Oxa-Terpenoids by Sesqui- and Diterpene Synthase-Mediated Biotransformations with 9-Oxy-FPP Ether Derivatives. Biochemistry 2024. doi:10.1021/acs.biochem.4c00589
• Payne, P. E.; Knobbe, L. N.; Chanton, P.; Zaugg, J.; Mortazavi, B.; Mason, O. U. Uncovering novel functions of the enigmatic, abundant, and active Anaerolineae in a salt marsh ecosystem. mSystems 2024, e0116224. doi:10.1128/msystems.01162-24
• Chaudhri, A. A.; Kakumu, Y.; Thiengmag, S.; Liu, J. C.-T.; Lin, G.-M.; Durusu, S.; Biermann, F.; Boeck, M.; Voigt, C. A.; Clardy, J.; Ueoka, R.; Walker, A. S.; Helfrich, E. J. N. Functional Redundancy and Dual Function of a Hypothetical Protein in the Biosynthesis of Eunicellane-Type Diterpenoids. ACS chemical biology 2024, 19, 2314–2322. doi:10.1021/acschembio.4c00413
• Ismael, S. B.; Ahmed, M. H.; Nakeeb, R. H. A.; Jassim, T. S. Secondary Metabolites in Plants: Their Role in Modulating the Immune Response to Viral Infections in Hosts. Stallion Journal for Multidisciplinary Associated Research Studies 2024, 3, 32–47. doi:10.55544/sjmars.3.5.5
• Hubrich, F.; Kandy, S. K.; Chepkirui, C.; Padhi, C.; Mordhorst, S.; Moosmann, P.; Zhu, T.; Gugger, M.; Chekan, J. R.; Piel, J. Ribosomal peptides with polycyclic isoprenoid moieties. Chem 2024, 10, 3224–3242. doi:10.1016/j.chempr.2024.07.026
• Terlouw, B. R.; Biermann, F.; Vromans, S. P. J. M.; Zamani, E.; Helfrich, E. J. N.; Medema, M. H. RAIChU: automating the visualisation of natural product biosynthesis. Journal of cheminformatics 2024, 16, 106. doi:10.1186/s13321-024-00898-x
• Payne, P. E.; Knobbe, L. N.; Chanton, P.; Zaugg, J.; Mortazavi, B.; Mason, O. U. Uncovering novel functions of the enigmatic, abundant and activeAnaerolineaein a salt marsh ecosystem. Cold Spring Harbor Laboratory 2024. doi:10.1101/2024.08.27.609934
• Velez-Haro, J. M.; Velázquez-Márquez, S.; Velázquez-Márquez, N. Natural Compounds for Inhibiting Oncogenic Microbiota: A Review of Their Therapeutic Applications. Pathogens Associated with the Development of Cancer in Humans; Springer Nature Switzerland, 2024; pp 369–410. doi:10.1007/978-3-031-62558-9_18
• de Matos, J. P.; Ribeiro, D. F.; da Silva, A. K.; de Paula, C. H.; Cordeiro, I. F.; Lemes, C. G. d. C.; Sanchez, A. B.; Rocha, L. C. M.; Garcia, C. C. M.; Almeida, N. F.; Alves, R. M.; de Abreu, V. A. C.; Varani, A. M.; Moreira, L. M. Diversity and potential functional role of phyllosphere-associated actinomycetota isolated from cupuassu (Theobroma grandiflorum) leaves: implications for ecosystem dynamics and plant defense strategies. Molecular genetics and genomics : MGG 2024, 299, 73. doi:10.1007/s00438-024-02162-1
• Boukouvala, S.; Kontomina, E.; Olbasalis, I.; Patriarcheas, D.; Tzimotoudis, D.; Arvaniti, K.; Manolias, A.; Tsatiri, M.-A.; Basdani, D.; Zekkas, S. Insights into the genomic and functional divergence of NAT gene family to serve microbial secondary metabolism. Scientific reports 2024, 14, 14905. doi:10.1038/s41598-024-65342-4
• Lawruk-Desjardins, C.; Storck, V.; Ponton, D. E.; Amyot, M.; Walsh, D. A. A genome catalogue of mercury-methylating bacteria and archaea from sediments of a boreal river facing human disturbances. Environmental microbiology 2024, 26, e16669. doi:10.1111/1462-2920.16669
• Cuervo, L.; Méndez, C.; Salas, J. A.; Olano, C.; Malmierca, M. G. Volatile communication in Actinobacteria: a language for secondary metabolism regulation. Microbial cell factories 2024, 23, 181. doi:10.1186/s12934-024-02456-4
• Yi, Y.; Liang, L.; de Jong, A.; Kuipers, O. P. A systematic comparison of natural product potential, with an emphasis on RiPPs, by mining of bacteria of three large ecosystems. Genomics 2024, 116, 110880. doi:10.1016/j.ygeno.2024.110880
• Jeong, E.; Kim, V.; Kim, C.; Lee, Y.-B.; Kim, D. Structural Insights into the Interaction of Terpenoids with Streptomyces avermitilis CYP107P2. Biomolecules & therapeutics 2024, 32, 474–480. doi:10.4062/biomolther.2024.045
• Tantillo, D. J. Energetics of proposed cyclizations for the biosynthesis of daphenoid A and artatrovirenols A and B. Tetrahedron Letters 2024, 143, 155113. doi:10.1016/j.tetlet.2024.155113
• Upadhyay, R.; Saini, R.; Shukla, P. K.; Tiwari, K. N. Role of secondary metabolites in plant defense mechanisms: a molecular and biotechnological insights. Phytochemistry Reviews 2024. doi:10.1007/s11101-024-09976-2
• Quesada, S.; Rosso, A. D.; Mascardi, F.; Soler-Rivero, V.; Aguilera, P.; Mascuka, S. N.; Boiro, A.; Arenielo, E.; Vijoditz, G.; Ferreyra-Mufarregue, L. R.; Caputo, M. F.; Cimolai, M. C.; Coluccio Leskow, F.; Penas-Steinhardt, A.; Belforte, F. S. Integrative analysis of systemic lupus erythematosus biomarkers: Role of fecal hsa-mir-223-3p and gut microbiota in transkingdom dynamics. Molecular immunology 2024, 171, 77–92. doi:10.1016/j.molimm.2024.05.004
• Hooe, S. L.; Green, C. M.; Susumu, K.; Stewart, M. H.; Breger, J. C.; Medintz, I. L. Optimizing the conversion of phosphoenolpyruvate to lactate by enzymatic channeling with mixed nanoparticle display. Cell reports methods 2024, 4, 100764. doi:10.1016/j.crmeth.2024.100764
• McBee, D. P.; Hulsey, Z. N.; Hedges, M. R.; Baccile, J. A. Biological Demands and Toxicity of Isoprenoid Precursors in Bacillus Subtilis Through Cell-Permeant Analogs of Isopentenyl Pyrophosphate and Dimethylallyl Pyrophosphate. Chembiochem : a European journal of chemical biology 2024, 25, e202400064. doi:10.1002/cbic.202400064
• Gennaiou, K.; Kelesidis, A.; Zografos, A. L. Climbing the Oxidase Phase Ladder by Using Dioxygen as the Sole Oxidant: The Case Study of Costunolide. Organic letters 2024, 26, 2934–2938. doi:10.1021/acs.orglett.4c00406

Explore citations to this article at