Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering

Eric J. N. Helfrich, Geng-Min Lin, Christopher A. Voigt and Jon Clardy
Beilstein J. Org. Chem. 2019, 15, 2889–2906. https://doi.org/10.3762/bjoc.15.283

Supporting Information

Supporting Information File 1: Additional figures and tables.
Format: PDF Size: 749.6 KB Download

Cite the Following Article

Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering
Eric J. N. Helfrich, Geng-Min Lin, Christopher A. Voigt and Jon Clardy
Beilstein J. Org. Chem. 2019, 15, 2889–2906. https://doi.org/10.3762/bjoc.15.283

How to Cite

Helfrich, E. J. N.; Lin, G.-M.; Voigt, C. A.; Clardy, J. Beilstein J. Org. Chem. 2019, 15, 2889–2906. doi:10.3762/bjoc.15.283

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 531.2 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • McBee, D. P.; Hulsey, Z. N.; Hedges, M. R.; Baccile, J. A. Biological Demands and Toxicity of Isoprenoid Precursors in Bacillus Subtilis Through Cell-Permeant Analogs of Isopentenyl Pyrophosphate and Dimethylallyl Pyrophosphate. Chembiochem : a European journal of chemical biology 2024, e202400064. doi:10.1002/cbic.202400064
  • Gennaiou, K.; Kelesidis, A.; Zografos, A. L. Climbing the Oxidase Phase Ladder by Using Dioxygen as the Sole Oxidant: The Case Study of Costunolide. Organic letters 2024, 26, 2934–2938. doi:10.1021/acs.orglett.4c00406
  • Paredes-Barrada, M.; Kopsiaftis, P.; Claassens, N. J.; van Kranenburg, R. Parageobacillus thermoglucosidasius as an emerging thermophilic cell factory. Metabolic engineering 2024, 83, 39–51. doi:10.1016/j.ymben.2024.03.001
  • Plett, J. M.; Wojtalewicz, D.; Plett, K. L.; Collin, S.; Kohler, A.; Jacob, C.; Martin, F. Sesquiterpenes of the ectomycorrhizal fungus Pisolithus microcarpus alter root growth and promote host colonization. Mycorrhiza 2024, 34, 69–84. doi:10.1007/s00572-024-01137-9
  • Chagas, F. O.; Garrido, L. M.; Conti, R.; Borges, R. M.; Bielinski, V. A.; Padilla, G.; Pupo, M. T. Unusual Sesquiterpenes from Streptomyces olindensis DAUFPE 5622. Journal of natural products 2024, 87, 491–500. doi:10.1021/acs.jnatprod.3c00752
  • Liu, W.; Tian, X.; Huang, X.; Malit, J. J. L.; Wu, C.; Guo, Z.; Tang, J.-W.; Qian, P.-Y. Discovery of P450-Modified Sesquiterpenoids Levinoids A-D through Global Genome Mining. Journal of natural products 2024. doi:10.1021/acs.jnatprod.3c01136
  • Frey, M.; Bathe, U.; Meink, L.; Balcke, G. U.; Schmidt, J.; Frolov, A.; Soboleva, A.; Hassanin, A.; Davari, M. D.; Frank, O.; Schlagbauer, V.; Dawid, C.; Tissier, A. Combinatorial biosynthesis in yeast leads to over 200 diterpenoids. Metabolic engineering 2024, 82, 193–200. doi:10.1016/j.ymben.2024.02.006
  • González-Hernández, R. A.; Valdez-Cruz, N. A.; Trujillo-Roldán, M. A. Factors that influence the extraction methods of terpenes from natural sources. Chemical Papers 2024, 78, 2783–2810. doi:10.1007/s11696-024-03339-z
  • Kwon, T.; Hovde, B. T. Global characterization of biosynthetic gene clusters in non-model eukaryotes using domain architectures. Scientific reports 2024, 14, 1534. doi:10.1038/s41598-023-50095-3
  • Cuervo, L.; Méndez, C.; Olano, C.; Malmierca, M. G. Volatilome: Smells like microbial spirit. Advances in Applied Microbiology; Elsevier, 2024. doi:10.1016/bs.aambs.2024.02.008
  • Muhammad, N.; Avila, F.; Nedashkovskaya, O. I.; Kim, S.-G. Three novel marine species of the genus Reichenbachiella exhibiting degradation of complex polysaccharides. Frontiers in microbiology 2023, 14, 1265676. doi:10.3389/fmicb.2023.1265676
  • Hooe, S. L.; Smith, A. D.; Dean, S. N.; Breger, J. C.; Ellis, G. A.; Medintz, I. L. Multienzymatic Cascades and Nanomaterial Scaffolding-A Potential Way Forward for the Efficient Biosynthesis of Novel Chemical Products. Advanced materials (Deerfield Beach, Fla.) 2023, 36, e2309963. doi:10.1002/adma.202309963
  • Patil, R. S.; Sharma, S.; Bhaskarwar, A. V.; Nambiar, S.; Bhat, N. A.; Koppolu, M. K.; Bhukya, H. TetR and OmpR family regulators in natural product biosynthesis and resistance. Proteins 2023. doi:10.1002/prot.26621
  • Ndao, A.; Adjallé, K. Overview of the Biotransformation of Limonene and α-Pinene from Wood and Citrus Residues by Microorganisms. Waste 2023, 1, 841–859. doi:10.3390/waste1040049
  • Le, V. V.; Ko, S.-R.; Oh, H.-M.; Ahn, C.-Y. Genomic Insights into Paucibacter aquatile DH15, a Cyanobactericidal Bacterium, and Comparative Genomics of the Genus Paucibacter. Journal of microbiology and biotechnology 2023, 33, 1615–1624. doi:10.4014/jmb.2307.07008
  • Hares, M. F.; Griffiths, B. E.; Johnson, F.; Nelson, C.; Haldenby, S.; Stewart, C. J.; Duncan, J. S.; Oikonomou, G.; Coombes, J. L. Specific pathway abundances in the neonatal calf faecal microbiome are associated with susceptibility to Cryptosporidium parvum infection: a metagenomic analysis. Animal microbiome 2023, 5, 43. doi:10.1186/s42523-023-00265-5
  • Scesa, P. D.; Schmidt, E. W. Biomimetic Approach to Diverse Coral Diterpenes from a Biosynthetic Scaffold. Angewandte Chemie (International ed. in English) 2023, 62, e202311406. doi:10.1002/anie.202311406
  • Scesa, P. D.; Schmidt, E. W. Biomimetic Approach to Diverse Coral Diterpenes from a Biosynthetic Scaffold. Angewandte Chemie 2023, 135. doi:10.1002/ange.202311406
  • Mendes, L. W.; Raaijmakers, J. M.; de Hollander, M.; Sepo, E.; Gómez Expósito, R.; Chiorato, A. F.; Mendes, R.; Tsai, S. M.; Carrión, V. J. Impact of the fungal pathogen Fusarium oxysporum on the taxonomic and functional diversity of the common bean root microbiome. Environmental microbiome 2023, 18, 68. doi:10.1186/s40793-023-00524-7
  • Ivanova, A. A.; Naumoff, D. G.; Kulichevskaya, I. S.; Meshcheriakova, A. A.; Dedysh, S. N. Paludisphaera mucosa sp. nov., a Novel Planctomycete of the Family Isosphaeraceae from a Boreal Fen. Microbiology 2023, 92, 483–492. doi:10.1134/s0026261723600921
Other Beilstein-Institut Open Science Activities