Extension of the 5-alkynyluridine side chain via C–C-bond formation in modified organometallic nucleosides using the Nicholas reaction

Renata Kaczmarek, Dariusz Korczyński, James R. Green and Roman Dembinski
Beilstein J. Org. Chem. 2020, 16, 1–8. https://doi.org/10.3762/bjoc.16.1

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Supporting Information File 1: 1H and 13C NMR spectra for compounds 2, 3, 4, 5, 6ac, and 7a,b,d.
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Extension of the 5-alkynyluridine side chain via C–C-bond formation in modified organometallic nucleosides using the Nicholas reaction
Renata Kaczmarek, Dariusz Korczyński, James R. Green and Roman Dembinski
Beilstein J. Org. Chem. 2020, 16, 1–8. https://doi.org/10.3762/bjoc.16.1

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Kaczmarek, R.; Korczyński, D.; Green, J. R.; Dembinski, R. Beilstein J. Org. Chem. 2020, 16, 1–8. doi:10.3762/bjoc.16.1

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  • Kowalski, K. Organometallic nucleosides—Synthesis, transformations, and applications. Coordination Chemistry Reviews 2021, 432, 213705. doi:10.1016/j.ccr.2020.213705
  • Monzón, D. M.; Betancort, J. M.; Martín, T.; Ramirez, M. A.; Martín, V. S.; Díaz, D. D. Intramolecular Nicholas Reaction Enables the Stereoselective Synthesis of Strained Cyclooctynes. Molecules (Basel, Switzerland) 2021, 26, 1629. doi:10.3390/molecules26061629
  • Kaczmarek, R.; Twardy, D. J.; Olson, T. L.; Korczyński, D.; Andrei, G.; Snoeck, R.; Dolot, R.; Wheeler, K. A.; Dembinski, R. Extension of furopyrimidine nucleosides with 5-alkynyl substituent: Synthesis, high fluorescence, and antiviral effect in the absence of free ribose hydroxyl groups. European journal of medicinal chemistry 2020, 209, 112884. doi:10.1016/j.ejmech.2020.112884
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