Supporting Information
The Supporting Information features 1) general procedures for the synthesis of all compounds and data analysis; 2) 1H NMR and 13C NMR of amidoxime, ethanone oxime and aldoxime carbamates; 3) Optimized structures of compounds 25–27 with the ab initio DFT computational methods, 4) DNA binding studies; 5) UV absorption spectra of all amidoxime, ethanone oxime and aldoxime carbamates; 6) Gel electrophoresis pictures of all amidoxime, ethanone oxime and aldoxime carbamate; 7) UV absorption spectra of amidoxime carbamates 11 and 12 under irradiation; 8) A computational study and photochemical aspects of compounds 11 and 12.
| Supporting Information File 1: Experimental part. | ||
| Format: PDF | Size: 3.3 MB | Download |
Cite the Following Article
p-Pyridinyl oxime carbamates: synthesis, DNA binding, DNA photocleaving activity and theoretical photodegradation studies
Panagiotis S. Gritzapis, Panayiotis C. Varras, Nikolaos-Panagiotis Andreou, Katerina R. Katsani, Konstantinos Dafnopoulos, George Psomas, Zisis V. Peitsinis, Alexandros E. Koumbis and Konstantina C. Fylaktakidou
Beilstein J. Org. Chem. 2020, 16, 337–350.
https://doi.org/10.3762/bjoc.16.33
How to Cite
Gritzapis, P. S.; Varras, P. C.; Andreou, N.-P.; Katsani, K. R.; Dafnopoulos, K.; Psomas, G.; Peitsinis, Z. V.; Koumbis, A. E.; Fylaktakidou, K. C. Beilstein J. Org. Chem. 2020, 16, 337–350. doi:10.3762/bjoc.16.33
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Presentation Graphic
| Picture with graphical abstract, title and authors for social media postings and presentations. | ||
| Format: PNG | Size: 346.5 KB | Download |
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Barakat, K.; Ragheb, M. A.; Soliman, M. H.; Abdelmoniem, A. M.; Abdelhamid, I. A. Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells. BMC chemistry 2024, 18, 183. doi:10.1186/s13065-024-01284-2
- Pei, H.-W.; Ye, K.; Shao, Y.; Chen, D.; Sun, Z.-Y.; Gong, T.; Liu, D.; Sun, K. Photopolymerization activated by photobase generators and applications: from photolithography to high-quality photoresists. Polymer Chemistry 2024, 15, 248–268. doi:10.1039/d3py00992k
- Yamamoto, A.; Tanaka, K.; Hashimoto, Y.; Morita, N.; Tamura, O. Intermolecular 1,3-Dipolar Cycloaddition Reaction of N-Carbamoyl Nitrones Generated by N-Selective Carbamoylation of Oximes with Isocyanates. Chemistry (Weinheim an der Bergstrasse, Germany) 2023, 30, e202303790. doi:10.1002/chem.202303790
- Panagopoulos, A.; Alipranti, K.; Mylona, K.; Paisidis, P.; Rizos, S.; Koumbis, A. E.; Roditakis, E.; Fylaktakidou, K. C. Exploration of the DNA Photocleavage Activity of O-Halo-phenyl Carbamoyl Amidoximes: Studies of the UVA-Induced Effects on a Major Crop Pest, the Whitefly Bemisia tabaci. DNA 2023, 3, 85–100. doi:10.3390/dna3020006
- Mikra, C.; Mitrakas, A.; Ghizzani, V.; Katsani, K. R.; Koffa, M.; Koukourakis, M.; Psomas, G.; Protti, S.; Fagnoni, M.; Fylaktakidou, K. C. Effect of Arylazo Sulfones on DNA: Binding, Cleavage, Photocleavage, Molecular Docking Studies and Interaction with A375 Melanoma and Non-Cancer Cells. International journal of molecular sciences 2023, 24, 1834. doi:10.3390/ijms24031834
- Polyzou, C. D.; Gkolfi, P.; Chasapis, C. T.; Bekiari, V.; Zianna, A.; Psomas, G.; Ondrej, M.; Tangoulis, V. Stimuli-responsive spin crossover nanoparticles for drug delivery and DNA-binding studies. Dalton transactions (Cambridge, England : 2003) 2022, 51, 12427–12431. doi:10.1039/d2dt01509a
- Akishina, E. A.; Dikusar, E. A.; Stepin, S. G.; Alekseyev, R. S.; Bumagin, N. A.; Potkin, V. I. Synthesis of 4-Acetyl- and 4-Benzoylpyridine Derivatives with 1,2-Azole Fragments. Russian Journal of General Chemistry 2022, 92, 759–765. doi:10.1134/s1070363222050036
- Mikra, C.; Bairaktari, M.; Petridi, M.-T.; Detsi, A.; Fylaktakidou, K. C. Green Process for the Synthesis of 3-Amino-2-methyl-quinazolin-4(3H)-one Synthones and Amides Thereof:DNA Photo-Disruptive and Molecular Docking Studies. Processes 2022, 10, 384. doi:10.3390/pr10020384
- Panagopoulos, A.; Balalas, T.; Mitrakas, A.; Vrazas, V.; Katsani, K. R.; Koumbis, A. E.; Koukourakis, M. I.; Litinas, K. E.; Fylaktakidou, K. C. 6-Nitro-Quinazolin-4(3H)-one Exhibits Photodynamic Effects and Photodegrades Human Melanoma Cell Lines. A Study on the Photoreactivity of Simple Quinazolin-4(3H)-ones. Photochemistry and photobiology 2021, 97, 826–836. doi:10.1111/php.13376
- Kaur, M.; Yusuf, M.; Malhi, D. S.; Sohal, H. S. Bis-dihydroisoxazolines: Synthesis, Structural Elucidation, Antimicrobial Evaluation, and DNA Photocleavage Assay. Current organic synthesis 2020, 17, 671–678. doi:10.2174/1570179417666200713181959
