Me3Al-mediated domino nucleophilic addition/intramolecular cyclisation of 2-(2-oxo-2-phenylethyl)benzonitriles with amines; a convenient approach for the synthesis of substituted 1-aminoisoquinolines

Krishna M. S. Adusumalli, Lakshmi N. S. Konidena, Hima B. Gandham, Krishnaiah Kumari, Krishna R. Valluru, Satya K. R. Nidasanametla, Venkateswara R. Battula and Hari K. Namballa
Beilstein J. Org. Chem. 2021, 17, 2765–2772. https://doi.org/10.3762/bjoc.17.186

Supporting Information

Supporting Information File 1: Experimental and analytical data.
Format: PDF Size: 2.1 MB Download

Cite the Following Article

Me3Al-mediated domino nucleophilic addition/intramolecular cyclisation of 2-(2-oxo-2-phenylethyl)benzonitriles with amines; a convenient approach for the synthesis of substituted 1-aminoisoquinolines
Krishna M. S. Adusumalli, Lakshmi N. S. Konidena, Hima B. Gandham, Krishnaiah Kumari, Krishna R. Valluru, Satya K. R. Nidasanametla, Venkateswara R. Battula and Hari K. Namballa
Beilstein J. Org. Chem. 2021, 17, 2765–2772. https://doi.org/10.3762/bjoc.17.186

How to Cite

Adusumalli, K. M. S.; Konidena, L. N. S.; Gandham, H. B.; Kumari, K.; Valluru, K. R.; Nidasanametla, S. K. R.; Battula, V. R.; Namballa, H. K. Beilstein J. Org. Chem. 2021, 17, 2765–2772. doi:10.3762/bjoc.17.186

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 10.3 MB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Ma, P.; Wang, Y.; Ma, N.; Wang, J. Alkaline-Metal-Promoted Divergent Synthesis of 1-Aminoisoquinolines and Isoquinolines. The Journal of organic chemistry 2024, 89, 1235–1240. doi:10.1021/acs.joc.3c02384
  • Sharma, H.; Kumar, M.; Sethi, A.; Poonam; Rathi, B. Metal-free construction of aminated isoquinoline frameworks from 2-(2-oxo-2-arylethyl) benzonitrile in an aqueous medium. Green Chemistry 2023, 25, 167–171. doi:10.1039/d2gc04044a
Other Beilstein-Institut Open Science Activities