¹⁹F NMR as a tool in chemical biology

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• Li, Y.; Huang, W.-S.; Zhang, L.; Su, D.; Xu, H.; Xue, X.-S. Prediction of 19F NMR chemical shift by machine learning. Artificial Intelligence Chemistry 2024, 2, 100043. doi:10.1016/j.aichem.2024.100043
• Roy, S.; Majee, P.; Sudhakar, S.; Mishra, S.; Kalia, J.; Pradeepkumar, P. I.; Srivatsan, S. G. Structural elucidation of HIV-1 G-quadruplexes in a cellular environment and their ligand binding using responsive 19F-labeled nucleoside probes. Chemical science 2024, 15, 7982–7991. doi:10.1039/d4sc01755b
• Monnie, C. M.; Hernández, I.; Meléndez‐Pacheco, R.; Bhinderwala, F.; Soloshonok, V. A.; Gronenborn, A. M.; Landa, A.; Oiarbide, M. Synthesis of 4,6‐Difluoro‐Tryptophan as a Probe for Protein 19F NMR. Advanced Synthesis & Catalysis 2024. doi:10.1002/adsc.202400031
• Ganguly, H. K.; Ludwig, B. A.; Tressler, C. M.; Bhatt, M. R.; Pandey, A. K.; Quinn, C. M.; Bai, S.; Yap, G. P. A.; Zondlo, N. J. 4,4-Difluoroproline as a Unique 19F NMR Probe of Proline Conformation. Biochemistry 2024, 63, 1131–1146. doi:10.1021/acs.biochem.3c00697
• Laxio Arenas, J.; Lesma, J.; Ha-Duong, T.; Ranjan Sahoo, B.; Ramamoorthy, A.; Tonali, N.; Soulier, J.-L.; Halgand, F.; Giraud, F.; Crousse, B.; Kaffy, J.; Ongeri, S. Composition and Conformation of Hetero- versus Homo-Fluorinated Triazolamers Influence their Activity on Islet Amyloid Polypeptide Aggregation. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 30, e202303887. doi:10.1002/chem.202303887
• Khan, M. F.; Hof, C.; Niemcova, P.; Murphy, C. D. Biotransformation of fluorinated drugs and xenobiotics by the model fungus Cunninghamella elegans. Methods in enzymology 2024, 696, 251–285. doi:10.1016/bs.mie.2023.12.016
• Costantino, A.; Pham, L. B. T.; Barbieri, L.; Calderone, V.; Ben-Nissan, G.; Sharon, M.; Banci, L.; Luchinat, E. Controlling the incorporation of fluorinated amino acids in human cells and its structural impact. Protein science : a publication of the Protein Society 2024, 33, e4910. doi:10.1002/pro.4910
• Chai, Z.; Li, C. In-Cell 19F NMR of Proteins: Recent Progress and Future Opportunities. Chemistry (Weinheim an der Bergstrasse, Germany) 2024, 30, e202303988. doi:10.1002/chem.202303988
• Matwani, K.; Cornish, J.; DeBenedictis, E. A.; Heller, G. T. Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications. Cold Spring Harbor Laboratory 2024. doi:10.1101/2024.02.12.579991
• Batarchuk, V.; Shepelytskyi, Y.; Grynko, V.; Kovacs, A. H.; Hodgson, A.; Rodriguez, K.; Aldossary, R.; Talwar, T.; Hasselbrink, C.; Ruset, I. C.; DeBoef, B.; Albert, M. S. Hyperpolarized Xenon-129 Chemical Exchange Saturation Transfer (HyperCEST) Molecular Imaging: Achievements and Future Challenges. International journal of molecular sciences 2024, 25, 1939. doi:10.3390/ijms25031939
• Frere, G. A.; Hasabnis, A.; Francisco, C. B.; Suleiman, M.; Alimowska, O.; Rahmatullah, R.; Gould, J.; Su, C. Y.-C.; Voznyy, O.; Gunning, P. T.; Basso, E. A.; Prosser, R. S. Next-Generation Tags for Fluorine Nuclear Magnetic Resonance: Designing Amplification of Chemical Shift Sensitivity. Journal of the American Chemical Society 2024, 146, 3052–3064. doi:10.1021/jacs.3c09730
• Gómez–Colín, D.; Santana-Martínez, I.; Bautista-Renedo, J. M.; Martínez-Otero, D.; Reyes, H.; Unnamatla, M. B.; González-Rivas, N.; Cuevas-Yañez, E. Synthesis, crystal and structural studies of 5-alkynyl-1,2,3-triazoles. Journal of Molecular Structure 2024, 1310, 138212. doi:10.1016/j.molstruc.2024.138212
• Simonet, B.; Herrscher, V.; Witjaksono, C.; Chaignon, P.; Massicot, F.; Vasse, J.-L.; Seemann, M.; Behr, J.-B. Carbohydrate-Templated Syntheses of Trifluoromethyl-Substituted MEP Analogues for the Study of the Methylerythritol Phosphate Pathway. The Journal of organic chemistry 2023, 88, 15832–15843. doi:10.1021/acs.joc.3c01910
• Prosser, R. S. A beginner's guide to 19F NMR and its role in drug screening. Canadian Journal of Chemistry 2023, 101, 758–764. doi:10.1139/cjc-2023-0028
• Rusakova, I. L.; Ukhanev, S. A.; Rusakov, Y. Y. On the relativistic effects on 19F nuclear magnetic resonance chemical shifts in the presence of iodine atoms. Journal of Fluorine Chemistry 2023, 271, 110188. doi:10.1016/j.jfluchem.2023.110188
• Baunis, H.; Pieber, B. Formal Radical Deoxyfluorination of Oxalate‐Activated Alcohols Triggered by the Selectfluor‐DMAP Charge‐Transfer Complex. European Journal of Organic Chemistry 2023, 26. doi:10.1002/ejoc.202300769
• Poškaitė, G.; Wheatley, D. E.; Wells, N.; Linclau, B.; Sinnaeve, D. Obtaining Pure 1H NMR Spectra of Individual Pyranose and Furanose Anomers of Reducing Deoxyfluorinated Sugars. The Journal of organic chemistry 2023, 88, 13908–13925. doi:10.1021/acs.joc.3c01503
• Gregorc, J.; Lensen, N.; Chaume, G.; Iskra, J.; Brigaud, T. Trifluoromethylthiolation of Tryptophan and Tyrosine Derivatives: A Tool for Enhancing the Local Hydrophobicity of Peptides. The Journal of organic chemistry 2023, 88, 13169–13177. doi:10.1021/acs.joc.3c01373
• Miles, S. A.; Nillama, J. A.; Hunter, L. Tinker, Tailor, Soldier, Spy: The Diverse Roles That Fluorine Can Play within Amino Acid Side Chains. Molecules (Basel, Switzerland) 2023, 28, 6192. doi:10.3390/molecules28176192
• Prosser, R. S.; Alonzi, N. A. Discerning conformational dynamics and binding kinetics of GPCRs by 19F NMR. Current opinion in pharmacology 2023, 72, 102377. doi:10.1016/j.coph.2023.102377

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