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EcoScale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters

Koen Van Aken, Lucjan Strekowski and Luc Patiny

Beilstein J. Org. Chem. 2006, 2, No. 3. https://doi.org/10.1186/1860-5397-2-3

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Koen Van Aken, Lucjan Strekowski and Luc Patiny

Beilstein J. Org. Chem. 2006, 2, No. 3. https://doi.org/10.1186/1860-5397-2-3

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Van Aken, K.; Strekowski, L.; Patiny, L. Beilstein J. Org. Chem. 2006, 2, No. 3. doi:10.1186/1860-5397-2-3

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TY  - JOUR
A1  - Van Aken, Koen
A1  - Strekowski, Lucjan
A1  - Patiny, Luc
T1  - EcoScale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters
JF  - Beilstein Journal of Organic Chemistry
PY  - 2006///
VL  - 2
SP  - 3
SN  - 1860-5397
DO  - 10.1186/1860-5397-2-3
PB  - Beilstein-Institut
JA  - Beilstein J. Org. Chem.
UR  - https://doi.org/10.1186/1860-5397-2-3
N2  - A novel post-synthesis analysis tool is presented which evaluates quality of the organic preparation based on yield, cost, safety, conditions and ease of workup/purification. The proposed approach is based on assigning a range of penalty points to these parameters. This semi-quantitative analysis can easily be modified by other synthetic chemists who may feel that some parameters should be assigned different relative penalty points. It is a powerful tool to compare several preparations of the same product based on safety, economical and ecological features.
ER  -

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aromatic	the word “aromatic”
aromatic aldehyde	the word “aromatic” OR “aldehyde”
+aromatic +aldehyde	both words “aromatic” AND “aldehyde”
+aromatic -aldehyde	the word “aromatic” but NOT “aldehyde”
“aromatic aldehyde”	the exact phrase “aromatic aldehyde”
benz*	words which begin with “benz”, such as “benzene” or “benzyl”
benz*yl	words that begin with “benz” and end with “yl”, such as “benzyl” or “benzoyl”
benzyl~	words that are close to the word “benzyl”, such as “benzoyl” (i.e., fuzzy search)