Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: A new route to pyrano[4,3-c]pyrazol-4(1H)-ones

Scholarly Works

• Lauridsen, J. M. V.; Kragh, R. R.; Lee, J.-W. Comprehensive Heterocyclic Chemistry IV - Pyrans and Their Benzo Derivatives: Synthesis. Comprehensive Heterocyclic Chemistry IV; Elsevier, 2022; pp 329–490. doi:10.1016/b978-0-12-818655-8.00005-6
• Ahmad, T.; Rasheed, T.; Hussain, M.; Rizwan, K. Emergence of 2-Pyrone and Its Derivatives, from Synthesis to Biological Perspective: An Overview and Current Status. Topics in current chemistry (Cham) 2021, 379, 38. doi:10.1007/s41061-021-00350-w
• Xiang, Y.; Rheingold, A. L.; Pentzer, E. Synthesis of Highly Functionalized 2-Pyranone from Silyl Ketene. ACS omega 2018, 3, 9419–9423. doi:10.1021/acsomega.8b01531
• Marangoni, M. A.; Bencke, C. E.; Bonacorso, H. G.; Martins, M. A. P.; Zanatta, N. Efficient synthesis of 6-aryl-4-trifluoromethyl/ethoxycarbonyl-2H-pyran-2-ones through self-condensation of penta-2,4-dienenitriles. Tetrahedron Letters 2018, 59, 121–124. doi:10.1016/j.tetlet.2017.12.003
• Üçüncü, M.; Cantürk, C.; Karakuş, E.; Zeybek, H.; Bozkaya, U.; Soydaş, E.; Şahin, E.; Emrullahoğlu, M. A rare γ-pyranopyrazole skeleton: design, one-pot synthesis and computational study. Organic & biomolecular chemistry 2016, 14, 7490–7494. doi:10.1039/c6ob01099g
• Fandrick, D. R.; Sanyal, S.; Kaloko, J.; Mulder, J. A.; Wang, Y.; Wu, L.; Lee, H.; Roschangar, F.; Hoffmann, M.; Senanayake, C. H. A Michael Equilibration Model To Control Site Selectivity in the Condensation toward Aminopyrazoles. Organic letters 2015, 17, 2964–2967. doi:10.1021/acs.orglett.5b01248
• Lee, J. S. Recent Advances in the Synthesis of 2-Pyrones. Marine drugs 2015, 13, 1581–1620. doi:10.3390/md13031581
• Shu, Z.; Li, W.; Wang, B. Pd/C‐Catalyzed Synthesis of Isoquinolones through CH Activation. ChemCatChem 2015, 7, 605–608. doi:10.1002/cctc.201403059
• Janin, Y. L. Preparation and chemistry of 3/5-halogenopyrazoles. Chemical reviews 2012, 112, 3924–3958. doi:10.1021/cr200427q
• Gorja, D. R.; Kumar, K. S.; Kandale, A.; Meda, C. L. T.; Parsa, K. V. L.; Mukkanti, K.; Pal, M. Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: a practical access via Pd/C-Cu catalysis. Bioorganic & medicinal chemistry letters 2012, 22, 2480–2487. doi:10.1016/j.bmcl.2012.02.008
• Vilkauskaitė, G.; Šačkus, A.; Holzer, W. Sonogashira‐Type Reactions with 5‐Chloro‐1‐phenyl‐1H‐pyrazole‐4‐carbaldehydes: A Straightforward Approach to Pyrazolo[4,3‐c]pyridines. European Journal of Organic Chemistry 2011, 2011, 5123–5133. doi:10.1002/ejoc.201100626
• Arbačiauskienė, E.; Vilkauskaitė, G.; Šačkus, A.; Holzer, W. Ethyl 3- and 5-Triflyloxy-1H-pyrazole-4-carboxylates in the Synthesis of Condensed Pyrazoles by Pd-Catalysed Cross-Coupling Reactions. European Journal of Organic Chemistry 2011, 2011, 1880–1890. doi:10.1002/ejoc.201001560

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