Supporting Information
Supporting information features a PDF document presenting details of studies using the bromoacetyl-OBt system 1 (R = Bt) and bromoacetyl-NHS system 1 (R = NHS), and associated experimental details, as well as Excel™ spreadsheets for the prediction of product outcomes and the optimisation of leaving group pKaH values of 2-S-thiophosphate esters with reference to controlling aminolysis over hydrolysis.
| Supporting Information File 1: Synthesis and application of bromoacetyl-OBt and NHS systems | ||
| Format: PDF | Size: 77.8 KB | Download |
| Supporting Information File 2: Prediction of product distribution using p-nitrophenyl ester 7 (R = pNP) | ||
| Format: XLS | Size: 410.5 KB | Download |
| Supporting Information File 3: Prediction of product distribution using m-nitrophenyl ester 7 (R = mNP) | ||
| Format: XLS | Size: 408.5 KB | Download |
| Supporting Information File 4: Optimisation of leaving group pKaH values of 2-S-thiophosphate esters | ||
| Format: XLS | Size: 444.0 KB | Download |
Cite the Following Article
Kinetic studies and predictions on the hydrolysis and aminolysis of esters of 2-S-phosphorylacetates
Milena Trmčić and David R. W. Hodgson
Beilstein J. Org. Chem. 2010, 6, 732–741.
https://doi.org/10.3762/bjoc.6.87
How to Cite
Trmčić, M.; Hodgson, D. R. W. Beilstein J. Org. Chem. 2010, 6, 732–741. doi:10.3762/bjoc.6.87
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