The Eschenmoser coupling reaction under continuous-flow conditions

Scholarly Works

• Mögel, M.; Heretsch, P. The Ramberg–Bäcklund Rearrangement and the Eschenmoser Coupling Reaction. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering; Elsevier, 2024. doi:10.1016/b978-0-323-96025-0.00026-0
• Arisawa, M.; Yamaguchi, M. Thiiranes and Thiirenes––Fused Ring Derivatives. Comprehensive Heterocyclic Chemistry IV; Elsevier, 2022; pp 413–435. doi:10.1016/b978-0-12-409547-2.14759-6
• Expósito, A.; Bai, Y.; Tchabanenko, K.; Rebrov, E. V.; Cherkasov, N. Process Intensification of Continuous-Flow Imine Hydrogenation in Catalyst-Coated Tube Reactors. Industrial & Engineering Chemistry Research 2019, 58, 4433–4442. doi:10.1021/acs.iecr.8b06058
• Adeyemi, A.; Bergman, J.; Brånalt, J.; Sävmarker, J.; Larhed, M. Continuous Flow Synthesis under High-Temperature/High-Pressure Conditions Using a Resistively Heated Flow Reactor. Organic Process Research & Development 2017, 21, 947–955. doi:10.1021/acs.oprd.7b00063
• Gao, Y.; Liu, Y.; Wei, L.; Wan, J.-P. Synthesis of enaminones containing diverse N,N-disubstitution via simple transamination: a study with sustainable catalyst-free operation. Research on Chemical Intermediates 2017, 43, 5547–5555. doi:10.1007/s11164-017-2946-z
• Pal, A.; Koduri, N. D.; Wang, Z.; Quiroz, E. L.; Chong, A.; Vuong, M.; Rajagopal, N.; Nguyen, M.; Roberts, K. P.; Hussaini, S. R. Copper-catalyzed chemoselective cross-coupling reaction of thioamides and α-diazocarbonyl compounds: Synthesis of enaminones. Tetrahedron Letters 2017, 58, 586–589. doi:10.1016/j.tetlet.2017.01.004
• Hussaini, S. R.; Chamala, R. R.; Wang, Z. The Eschenmoser sulfide contraction method and its application in the synthesis of natural products. Tetrahedron 2015, 71, 6017–6086. doi:10.1016/j.tet.2015.06.026
• Singh, S.; Schober, A.; Gross, G. A. Direct access to 3-substituted 1,4-oxathiepino[5,6-b]pyridine-5-one through one-pot substitution cyclization reaction of 2-mercapto-3-nicotinic acid with α-bromo ketones. Tetrahedron Letters 2014, 55, 358–361. doi:10.1016/j.tetlet.2013.11.030
• Braverman, S.; Cherkinsky, M. 3.18 The Ramberg–Bäcklund Rearrangement and the Eschenmoser Coupling Reaction. Comprehensive Organic Synthesis II; Elsevier, 2014; pp 887–943. doi:10.1016/b978-0-08-097742-3.00324-4
• Sizonenko, E. S.; Kobrakov, I. K.; Popov, V. Y.; Suikov, S. Y.; Bogza, S. L. Synthesis of 2-R-2-(1-Aryl-7,8-Dimethoxy-5H-2,3-Benzodiazepin-4-yl)Acetic Acid Esters in the Eschenmoser Reaction. Chemistry of Heterocyclic Compounds 2013, 49, 1352–1357. doi:10.1007/s10593-013-1384-0
• Koduri, N. D.; Hileman, B.; Cox, J. D.; Scott, H.; Hoang, P.; Robbins, A.; Bowers, K.; Tsebaot, L.; Miao, K.; Castaneda, M.; Coffin, M.; Wei, G.; Claridge, T. D. W.; Roberts, K. P.; Hussaini, S. R. Acceleration of the Eschenmoser coupling reaction by sonication: efficient synthesis of enaminones. RSC Adv. 2013, 3, 181–188. doi:10.1039/c2ra22033d
• Murai, T.; Mutoh, Y. Thioamides and Thioformamides for Sequential Reactions with Organolithium and Grignard Reagents. Chemistry Letters 2011, 41, 2–8. doi:10.1246/cl.2012.2
• Rueping, M.; Bootwicha, T.; Baars, H.; Sugiono, E. Continuous-flow hydration–condensation reaction: Synthesis of α,β-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst. Beilstein journal of organic chemistry 2011, 7, 1680–1687. doi:10.3762/bjoc.7.198
• Glasnov, T. N. Highlights from the Flow Chemistry Literature 2011 (Part 2). Journal of Flow Chemistry 2011, 1, 90–96. doi:10.1556/jfchem.2011.00018

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