Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents

Scholarly Works

• Dhayalan, V.; Dodke, V. S.; Pradeep Kumar, M.; Korkmaz, H. S.; Hoffmann-Röder, A.; Amaladass, P.; Dandela, R.; Dhanusuraman, R.; Knochel, P. Recent synthetic strategies for the functionalization of fused bicyclic heteroaromatics using organo-Li, -Mg and -Zn reagents. Chemical Society reviews 2024. doi:10.1039/d4cs00369a
• Alam, M. M.; Varala, R.; Seema, V. Zinc Acetate in Organic Synthesis and Catalysis: A Review. Mini-Reviews in Organic Chemistry 2024, 21, 555–587. doi:10.2174/1570193x20666230507213511
• Younes, E. A.; Al-Snaid, A. M.; Abu-Safieh, K. A.; Salami, F.; Aljaar, N.; Zhao, Y. Synthesis and characterization of 2-(anthracene-9-yl)-4,5-diphenyl-1H-imidazole derivatives as environmentally sensitive fluorophores. RSC advances 2024, 14, 23511–23519. doi:10.1039/d4ra03735a
• Chaisan, N.; Yew Kun Tan, E.; Chiba, S. Hydroalkylation of 1,1‐Diarylalkenes Mediated by Magnesium Hydride in Ethereal Solvents. Helvetica Chimica Acta 2024, 107. doi:10.1002/hlca.202300212
• Dhayalan, V.; Sharma, D.; Chatterjee, R.; Dandela, R. Functionalization of Pyridine and Quinoline Scaffolds by Using Organometallic Li‐, Mg‐ and Zn‐Reagents. European Journal of Organic Chemistry 2023, 26. doi:10.1002/ejoc.202300285
• Bruneau, C.; Gramage‐Doria, R. doi:10.1002/9781119774167.ch9
• Li, G.; Jiang, B.; Wang, J.-Y.; Hao, W.-J. Catalytic Benzannulation Reactions of Enynones for Accessing Heterocycle-Incorporating Diarylmethanes. Synlett 2022, 34, 243–248. doi:10.1055/a-1971-6187
• Khatavi, S. Y.; Kamanna, K. Facile and greener method synthesis of pyrano[2,3-d]pyrimidine-2,4,7-triones: Electrochemical and biological activity evaluation studies. Journal of Molecular Structure 2022, 1250, 131708. doi:10.1016/j.molstruc.2021.131708
• Wren, S. P. Tricyclic systems : central carbocyclic ring with fused five- and six-membered rings. Comprehensive Heterocyclic Chemistry IV; Elsevier, 2022; pp 1003–1019. doi:10.1016/b978-0-12-409547-2.14896-6
• Fazekas, E.; Lowy, P. A.; Rahman, M. A.; Garden, J. A. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering - Zinc Reagents in Organic Synthesis. Comprehensive Organometallic Chemistry IV; Elsevier, 2022; pp 193–304. doi:10.1016/b978-0-12-820206-7.00090-1
• Watanabe, K.; Pang, J. H.; Takita, R.; Chiba, S. Generation of organo-alkaline earth metal complexes from non-polar unsaturated molecules and their synthetic applications. Chemical science 2021, 13, 27–38. doi:10.1039/d1sc05724c
• Kang, K.; Loud, N. L.; DiBenedetto, T. A.; Weix, D. J. A General, Multimetallic Cross-Ullmann Biheteroaryl Synthesis from Heteroaryl Halides and Heteroaryl Triflates. Journal of the American Chemical Society 2021, 143, 21484–21491. doi:10.1021/jacs.1c10907
• Chandrasekaran, R.; Pulikkottil, F. T.; Elama, K. S.; Rasappan, R. Direct synthesis and applications of solid silylzinc reagents. Chemical science 2021, 12, 15719–15726. doi:10.1039/d1sc06038d
• Peng, Z.; Yu, C.; Wang, Y.; Wei, D.; Jiang, C. Direct C–H Arylation and Alkylation of Electron-Deficient Heteroaromatic Compounds with Organozinc Reagents. Organometallics 2021, 40, 3678–3688. doi:10.1021/acs.organomet.1c00505
• Kajimoto, C.; Yamada, S.; Konno, T. Novel multi-functionalized fluorine-containing organometallics: Preparation and applications of tetrafluoroethylenated zinc reagent. Journal of Fluorine Chemistry 2021, 245, 109781. doi:10.1016/j.jfluchem.2021.109781
• Mahmudov, K. T.; da Silva, M. F. C. G.; Gurbanov, A. V.; Pombeiro, A. J. L. Synthetic Approaches to Nonaromatic Nitrogen Heterocycles; Wiley, 2020; pp 767–787. doi:10.1002/9781119708841.ch24
• Bhaskaran, S.; Padusha, M. S. A.; Sajith, A. M. Application of Palladium Based Precatalytic Systems in the Suzuki-Miyaura Cross-Coupling Reactions of Chloro- Heterocycles. ChemistrySelect 2020, 5, 9005–9016. doi:10.1002/slct.202002357
• de Almeida Santos, G.; Dhoke, G. V.; Davari, M. D.; Ruff, A. J.; Schwaneberg, U. Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles. International journal of molecular sciences 2019, 20, 3353. doi:10.3390/ijms20133353
• O'Donnell, M. J. Benzophenone Schiff bases of glycine derivatives: Versatile starting materials for the synthesis of amino acids and their derivatives. Tetrahedron 2019, 75, 3667–3696. doi:10.1016/j.tet.2019.03.029
• Gandeepan, P.; Müller, T.; Zell, D.; Cera, G.; Warratz, S.; Ackermann, L. 3d Transition Metals for C-H Activation. Chemical reviews 2018, 119, 2192–2452. doi:10.1021/acs.chemrev.8b00507

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