Supporting Information
Supporting Information File 1: Complete experimental procedures and characterization. | ||
Format: PDF | Size: 1.1 MB | Download |
Supporting Information File 2: Figures of 1H and 13C NMR spectra. | ||
Format: PDF | Size: 4.9 MB | Download |
Cite the Following Article
The multicomponent approach to N-methyl peptides: total synthesis of antibacterial (–)-viridic acid and analogues
Ricardo A. W. Neves Filho, Sebastian Stark, Bernhard Westermann and Ludger A. Wessjohann
Beilstein J. Org. Chem. 2012, 8, 2085–2090.
https://doi.org/10.3762/bjoc.8.234
How to Cite
Neves Filho, R. A. W.; Stark, S.; Westermann, B.; Wessjohann, L. A. Beilstein J. Org. Chem. 2012, 8, 2085–2090. doi:10.3762/bjoc.8.234
Download Citation
Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window
below.
Citation data in RIS format can be imported by all major citation management software, including EndNote,
ProCite, RefWorks, and Zotero.
Citations to This Article
Up to 20 of the most recent references are displayed here.
Scholarly Works
- Sebastian, S. K.; Stellance, A.; Sadanandan, S. V. Leveraging the Potential of Iqbal MCR: An Efficient Synthetic Route to Structurally Complex Tripeptidyl Ketones via Sequential Iqbal‐3CR/Ugi‐4CR. ChemistrySelect 2024, 9. doi:10.1002/slct.202403771
- Zhang, W.; Tang, P.; Abubaker, M. A.; Hu, G.-H.; Chen, F.-E. Advances of Ugi reaction in natural product synthesis. Green Synthesis and Catalysis 2024. doi:10.1016/j.gresc.2024.08.004
- Sebastian, S.; Rohila, Y.; Meenakshi; Prakash, S.; Kumar, A.; Sengupta, S.; Kumar, D.; Ansari, A.; Gupta, M. K. Atom-economical synthesis, antimicrobial assessment, and molecular dynamics of indole-derived peptidomimetics for improved therapeutic insights. Journal of Molecular Structure 2024, 1318, 139211. doi:10.1016/j.molstruc.2024.139211
- Morlacci, V.; Arcadi, A.; Aschi, M.; Chiarini, M.; Demitri, N.; Lamba, D.; Momoli, C.; Palombi, L.; Vece, V. Diastereoselective Synthesis of High Functionalized 4‐Imidazolidinone‐Tetrahydro‐β‐Carboline Hybrids via Divergent Post‐Ugi Transformation. Advanced Synthesis & Catalysis 2024, 366, 2376–2381. doi:10.1002/adsc.202400133
- Larghi, E. L.; Bracca, A. B. J.; Simonetti, S. O.; Kaufman, T. S. Recent developments in the total synthesis of natural products using the Ugi multicomponent reactions as the key strategy. Organic & biomolecular chemistry 2024, 22, 429–465. doi:10.1039/d3ob01837g
- Quazi, S.; Rashid, M. T.; Malik, J. A.; Gavas, S. The Discovery of Novel Antimicrobial Agents through the Application of Isocyanide-Based Multicomponent Reactions. Antibiotics (Basel, Switzerland) 2023, 12, 849. doi:10.3390/antibiotics12050849
- Tandi, M.; Sundriyal, S. Recent trends in the design of antimicrobial agents using Ugi-multicomponent reaction. Journal of the Indian Chemical Society 2021, 98, 100106. doi:10.1016/j.jics.2021.100106
- Fouad, M. A.; Abdel-Hamid, H.; Ayoup, M. S. Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications. RSC advances 2020, 10, 42644–42681. doi:10.1039/d0ra07501a
- Padilla-Salinas, R.; Anderson, R.; Sakaniwa, K.; Zhang, S.; Nordeen, P.; Lu, C.; Shimizu, T.; Yin, H. Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8. Journal of medicinal chemistry 2019, 62, 10221–10244. doi:10.1021/acs.jmedchem.9b01201
- Ayoup, M. S.; Fouad, M. A.; Abdel-Hamid, H.; Ramadan, E. S.; Abu-Serie, M. M.; Noby, A.; Teleb, M. Battle tactics against MMP-9; discovery of novel non-hydroxamate MMP-9 inhibitors endowed with PI3K/AKT signaling attenuation and caspase 3/7 activation via Ugi bis-amide synthesis. European journal of medicinal chemistry 2019, 186, 111875. doi:10.1016/j.ejmech.2019.111875
- Sarojini, V.; Cameron, A. J.; Varnava, K. G.; Denny, W. A.; Sanjayan, G. J. Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function. Chemical reviews 2019, 119, 10318–10359. doi:10.1021/acs.chemrev.8b00737
- Heravi, M. M.; Zadsirjan, V.; Dehghani, M.; Ahmadi, T. Towards click chemistry: Multicomponent reactions via combinations of name reactions. Tetrahedron 2018, 74, 3391–3457. doi:10.1016/j.tet.2018.04.076
- Kaluđerović, G. N.; Abbas, M.; Kautz, H. C.; Wadaan, M. A. M.; Lennicke, C.; Seliger, B.; Wessjohann, L. A. Methionine and seleno-methionine type peptide and peptoid building blocks synthesized by five-component five-center reactions. Chemical communications (Cambridge, England) 2017, 53, 3777–3780. doi:10.1039/c7cc00399d
- Shaaban, S.; Negm, A.; Ashmawy, A. M.; Ahmed, D. M.; Wessjohann, L. A. Combinatorial synthesis, in silico, molecular and biochemical studies of tetrazole-derived organic selenides with increased selectivity against hepatocellular carcinoma. European journal of medicinal chemistry 2016, 122, 55–71. doi:10.1016/j.ejmech.2016.06.005
- Brauer, M. C. N.; Filho, R. A. W. N.; Westermann, B.; Heinke, R.; Wessjohann, L. A. Synthesis of antibacterial 1,3-diyne-linked peptoids from an Ugi-4CR/Glaser coupling approach. Beilstein journal of organic chemistry 2015, 11, 25–30. doi:10.3762/bjoc.11.4
- de Fátima S. Barreto, A.; Vercillo, O. E.; Wessjohann, L. A.; Andrade, C. K. Z. Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids. Beilstein journal of organic chemistry 2014, 10, 1017–1022. doi:10.3762/bjoc.10.101