Synthesis of 5-(ethylsulfonyl)-2-methoxyaniline: An important pharmacological fragment of VEGFR2 and other inhibitors

Scholarly Works

• Liashuk, O. S.; Andriashvili, V. A.; Tolmachev, A. O.; Grygorenko, O. O. Chemoselective Reactions of Functionalized Sulfonyl Halides. Chemical record (New York, N.Y.) 2023, 24, e202300256. doi:10.1002/tcr.202300256
• Hsueh, N.; Chen, K.; Chang, M. One‐pot Construction of Dibenzooxabicyclo[5.5.0]dodecanes. Advanced Synthesis & Catalysis 2022, 364, 4110–4121. doi:10.1002/adsc.202200914
• Johnson, H.; Gleason, C.; Klug, T.; Schmid, C.; Schioldager, R.; DiBernardo, C.; Eagon, S. Improved Synthesis of 5-Ethylsulfonyl-2-methoxyaniline. Organic Preparations and Procedures International 2022, 54, 435–439. doi:10.1080/00304948.2022.2072154
• Murugan Sreedevi, S.; Vinod, S. M.; Krishnan, A.; Perumal, T.; Chinnadurai, R.; Rajendran, K. Photophysical and molecular docking approach on the interaction of water-soluble simple keto sugar with acridinedione dyes. Results in Chemistry 2022, 4, 100680. doi:10.1016/j.rechem.2022.100680
• Bayrak, C.; Yildizhan, G.; Kilinc, N.; Durdagi, S.; Menzek, A. Synthesis and Aldose Reductase Inhibition Effects of Novel N-Benzyl-4-Methoxyaniline Derivatives. Chemistry & biodiversity 2021, 19, e202100530. doi:10.1002/cbdv.202100530
• Xin, Y.-H.; Guo, Y.-Q.; Zhang, X.-G.; Deng, C.-L. Palladium-Catalyzed Methylsulfonylation of Alkyl Halides Using Dimethyl Sulfite as SO2 Surrogate and Methyl Source. The Journal of organic chemistry 2021, 86, 17496–17503. doi:10.1021/acs.joc.1c02188
• Gholami, A.; Mokhtary, M.; Nikpassand, M. Choline chloride/Oxalic acid (ChCl/Oxa) catalyzed one-pot synthesis of novel azo and sulfonated pyrimido[4,5-b]quinoline derivatives. Dyes and Pigments 2020, 180, 108453. doi:10.1016/j.dyepig.2020.108453
• Sharafi-Kolkeshvandi, M.; Nematollahi, D.; Nikpour, F.; Salahifar, E. Electrochemical synthesis of 1-N-phenyl-4-(sulfonyl)benzene-1,2-diamine derivatives: a mild and regioselective protocol. New Journal of Chemistry 2016, 40, 5442–5447. doi:10.1039/c5nj03514g
• Pal, K. B.; Sarkar, V.; Mukhopadhyay, B. Hydrogen bonding-induced conformational change in a crystalline sugar derivative†. CrystEngComm 2016, 18, 1156–1163. doi:10.1039/c5ce01893e
• Vojtičková, M.; Dobiaš, J.; Hanquet, G.; Addová, G.; Cetin-Atalay, R.; Yildirim, D.; Boháč, A. Ynamide Click chemistry in development of triazole VEGFR2 TK modulators. European journal of medicinal chemistry 2015, 103, 105–122. doi:10.1016/j.ejmech.2015.08.012
• Jereb, M.; Dolenc, D. Electrophilic trifluoromethylthiolation of thiols with trifluoromethanesulfenamide. RSC Advances 2015, 5, 58292–58306. doi:10.1039/c5ra07316b
• Yunlong, S.; Ling, W.; Qian, C.; Tao, M.; Liao, Z.-T.; Chen, X. A new procedure for the synthesis of 2-[(4-dodecyloxyphenyl)sulfonyl]butanoic acid. Chemical Papers 2015, 69, 1237–1243. doi:10.1515/chempap-2015-0125
• Lintnerová, L.; Kovacikova, L.; Hanquet, G.; Boháč, A. Selected Methodologies Convenient for the Synthesis of N,5‐Diaryloxazole‐2‐amine Pharmacophore. Journal of Heterocyclic Chemistry 2014, 52, 425–439. doi:10.1002/jhet.2063
• Lintnerová, L.; García-Caballero, M.; Gregáň, F.; Melicherčík, M.; Quesada, A. R.; Dobiaš, J.; Lác, J.; Sališová, M.; Boháč, A. A development of chimeric VEGFR2 TK inhibitor based on two ligand conformers from PDB: 1Y6A complex – Medicinal chemistry consequences of a TKs analysis. European journal of medicinal chemistry 2013, 72, 146–159. doi:10.1016/j.ejmech.2013.11.023
• Emmett, E. J.; Hayter, B. R.; Willis, M. C. Palladium‐Catalyzed Three‐Component Diaryl Sulfone Synthesis Exploiting the Sulfur Dioxide Surrogate DABSO. Angewandte Chemie 2013, 125, 12911–12915. doi:10.1002/ange.201305369
• Emmett, E. J.; Hayter, B. R.; Willis, M. C. Palladium‐Catalyzed Three‐Component Diaryl Sulfone Synthesis Exploiting the Sulfur Dioxide Surrogate DABSO. Angewandte Chemie (International ed. in English) 2013, 52, 12679–12683. doi:10.1002/anie.201305369

Explore citations to this article at