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Beilstein J. Org. Chem. 2024, 20, 1785–1793, doi:10.3762/bjoc.20.157
Graphical Abstract
Scheme 1: Examples of fluorination using hypervalent iodine(III) reagents 1 and 2.
Scheme 2: Preparations and reactions of hypervalent iodine(V) fluorides.
Figure 1: Bicyclic difluoro(aryl)-λ5-iodanes.
Scheme 3: Attempted oxidative fluorination of hypervalent iodine(III) amides.
Scheme 4: Synthesis of methyl(trifluoromethyl)fluoroiodane 15.
Scheme 5: Synthesis of bis(trifluoromethyl)fluoroiodane 19.
Scheme 6: Reaction of phenylmagnesium bromide with bis(trifluoromethyl)trifluoroiodane 22.
Figure 2: Molecular structure of difluoroiodane 6 showing 50% displacement ellipsoids.
Figure 3: Stability of difluoroiodane 6 in air in dry CD3CN (blue line), dry CDCl3 with 2.4 equivalents of dr...
Figure 4: Order of hydrolytic stability for the four hypervalent iodine(V) fluorides.