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1 article(s) from Friedrich, Leon M

Orthogonal photoswitching of heterobivalent azobenzene glycoclusters: the effect of glycoligand orientation in bacterial adhesion

Leon M. Friedrich and
Thisbe K. Lindhorst

Beilstein J. Org. Chem. 2025, 21, 736–748, doi:10.3762/bjoc.21.57

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Figure 1: Cartoon of the photoswitchable glycoconjugates investigated in this account. The previously describ...

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Scheme 1: Synthesis of the homobivalent azobenzene glycocluster 6αMan3αMan 2. Reagents and conditions: a) BF₃...

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Scheme 2: Synthesis of the antennas 6βGlc 3 and 3αMan 4 (A), and 6αMan 5 (B). Reagents and conditions: a) DTT...

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Figure 2: A: Wavelength-selective photoswitching of the α-ᴅ-mannopyranosyloxy-AB and -ABF₄ antennas comprised...

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Figure 3: Comparison of the inhibitory potencies of 1, 2, 4, and 5 in the different isomeric states. The depi...

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Figure 4: Three-dimensional representation of the superimposed most stable ligand–protein complexes from IFD ...

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Published 08 Apr 2025

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