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Beilstein J. Org. Chem. 2024, 20, 1198–1206, doi:10.3762/bjoc.20.102
Graphical Abstract
Scheme 1: Ring cleavage and ring rearrangement reactions in the biosynthesis of atypical angucyclines.
Figure 1: HPLC traces of reaction mixtures of AlpG, AlpJ, Flu17, and JadG. (a) standards of prejadomycin (9),...
Figure 2: HPLC traces of reactions of JadG, AlpJ, or Flu17 quenched by SOD. (a) 8 + JadG + ʟ-isoleucine; (b) 8...
Scheme 2: Proposed catalytic mechanism of cofactor-independent AlpJ-family oxygenases.
Beilstein J. Org. Chem. 2024, 20, 852–858, doi:10.3762/bjoc.20.77
Figure 1: Structures of spiroviolene and related natural products.
Scheme 1: Possible cyclization mechanisms for spiroviolene (1) and related natural products. A) Revised cycli...
Figure 2: Heterologous production of spiroviolene using the isopentenol utilization pathway. A) Gas chromatog...
Scheme 2: Derivatization of spiroviolene for X-ray crystallography. A) Hydroboration/oxidation reaction of sp...