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Beilstein J. Org. Chem. 2024, 20, 2655–2667, doi:10.3762/bjoc.20.223
Graphical Abstract
Figure 1: Some 2-hydroxybenzophenone derivatives with varied activities.
Figure 2: Decarbonylation–oxidation of lactones.
Scheme 1: Synthesis of 3-arylbenzofuran-2(3H)-ones.
Scheme 2: Synthesis of 2-hydroxybenzophenones.
Figure 3: The ORTEP view of the compounds 4ja, 4fb, and 4ma.
Scheme 3: Gram-scale experiment.
Scheme 4: Control experiments.
Figure 4: Partial 1H NMR spectra of the aliquots (taken at different time intervals) from the reaction mixtur...
Figure 5: Plausible mechanism for the transition-metal-free decarbonylation–oxidation.
Figure 6: UV–vis absorption spectra of selected synthesized compounds 4aa, 4cb, 4eb, and 4fb from 225–500 nm.