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Beilstein J. Org. Chem. 2015, 11, 2763–2773, doi:10.3762/bjoc.11.297
Graphical Abstract
Figure 1: Structures of (A) hesperetin, (B) naringenin and (C) the two cyclodextrins: β-CD and DM-β-CD with t...
Figure 2: Phase solubility study of hesperetin (upper panel) and naringenin (lower panel) with β-CD or RAMEB ...
Figure 3: DSC thermograms of hesperetin (left) and naringenin (right) (A) β-CD, (B) RAMEB, (C) Free flavanone...
Figure 4: The dissolution diagram at 37 °C in water of the free flavanones and their complexes. (A) hespereti...
Figure 5: The influence of flavanones and their complexes on IL-6 secretion from LPS-stimulated macrophages.
Figure 6: Cytotoxicity of free flavanones and their inclusion complexes on different cancer cell lines.
Figure 7: The docked orientations of hesperetin in the hydrophobic cavity of (A) β-CD and (B) DM-β-CD and top...