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Beilstein J. Org. Chem. 2024, 20, 1560–1571, doi:10.3762/bjoc.20.139
Graphical Abstract
Figure 1: Schematic of (a) a PEM reactor and (b) MEA.
Scheme 1: Plausible mechanism for the reduction of 1a leading to benzylamine 2a and dibenzylamine 3a.
Scheme 2: Electrochemical reduction of cyanoarenes under optimal conditions. Reaction conditions: anode catal...
Scheme 3: Scope of the electrochemical reduction of nitroarenes. Reaction conditions: anode catalyst, Pt/C; c...
Figure 2: Hypothesis of the trap of quinoline on membrane and tetrahydroquinoline and the effect of adding an...
Figure 3: Recycled use of MEA for the electroreduction of 6a in the presence of PTSA (0.10 equiv). Reaction c...
Figure 4: Recycled use of MEA for the electroreduction of 6a in the presence of PPTS (0.10 equiv). Reaction c...
Scheme 4: Scope of the electroreduction of 6 in the presence of PTSA (0.10 equiv). Reaction conditions: anode...
Scheme 5: a) Large scale synthesis of 7a and b) electoreduction of 6a using H2SO4 as a proton source.
Scheme 6: Scope of the electroreduction of 6 in the presence of PTSA (1 equiv). Reaction conditions: anode ca...
Beilstein J. Org. Chem. 2024, 20, 264–271, doi:10.3762/bjoc.20.27
Figure 1: Application of amidyl radical species generated by PCET.
Figure 2: (A) Effect of phosphate base on the cyclic voltammogram of 1. (B) Cyclic voltammograms of 1 in the ...
Figure 3: Plausible models illustrating the size effect of the hydrogen bond complex on the interaction effic...
Figure 4: Plausible mechanism for the inter-/intramolecular hydroamination of 1.
Beilstein J. Org. Chem. 2022, 18, 350–359, doi:10.3762/bjoc.18.39
Figure 1: Piperidine and pyrrolidine rings in biologically active compounds.
Scheme 1: Conventional synthetic routes for piperidine derivatives.
Scheme 2: Synthesis of 1,2-diphenylpiperidine (3a) by the electroreductive cyclization mechanism.
Figure 2: Schematic diagram of the electroreductive cyclization for the synthesis of 1,2-diphenylpiperidine (...
Figure 3: Yield of 3a for each fraction sample in the continuous flow reductive cyclization.