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Beilstein J. Org. Chem. 2024, 20, 1341–1347, doi:10.3762/bjoc.20.118
Graphical Abstract
Scheme 1: Ullmann and Ullmann-type homo-coupling reactions.
Scheme 2: Rh-catalyzed homo-coupling reactions.
Scheme 3: Rh-catalyzed homo-coupling reaction by using Grignard reagents.
Scheme 4: Rh-catalyzed one-pot Ullmann-type reaction with bromobenzene under optimized reaction conditions.
Figure 1: Scope and limitations for the Rh-catalyzed one-pot Ullmann-type reaction. Conditions: a) The reacti...
Figure 2: Tentative reaction mechanism.
Scheme 5: Synthesis of compound 10n as a candidate for an integrin inhibitor.