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2 article(s) from Xie, Juan

Photoswitchable glycoligands targeting Pseudomonas aeruginosa LecA

Yu Fan,
Ahmed El Rhaz,
Stéphane Maisonneuve,
Emilie Gillon,
Maha Fatthalla,
Franck Le Bideau,
Guillaume Laurent,
Samir Messaoudi,
Anne Imberty and
Juan Xie

Beilstein J. Org. Chem. 2024, 20, 1486–1496, doi:10.3762/bjoc.20.132

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Graphical Abstract

Figure 1: (A) Selected monovalent inhibitors for PA LecA and (B) designed general structure of photoswitchabl...

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Scheme 1: Synthesis of photoswitchable LecA inhibitors. Reagents and conditions: (i) DMC, Et₃N, H₂O, −10 °C t...

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Figure 2: (Left) Absorption spectra and (right) fatigue resistance of 1 under alternated 370/485 nm irradiati...

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Figure 3: ¹H NMR (400 MHz) spectra of E-1 (black line), PSS₃₇₀ (red line), PSS₄₈₅ (blue line) in D₂O/DMSO-d₆ ...

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Figure 4: ITC titration of LecA with E- (up) and Z-isomers (bottom) of compounds 1–5 in Tris buffer containin...

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Figure 5: (A) Enthalpy–entropy compensation plot of compounds 1–5 from ITC analysis. The dotted green line re...

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Full Research Paper

Published 03 Jul 2024

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Multichromophoric sugar for fluorescence photoswitching

Stéphane Maisonneuve,
Rémi Métivier,
Pei Yu,
Keitaro Nakatani and
Juan Xie

Beilstein J. Org. Chem. 2014, 10, 1471–1481, doi:10.3762/bjoc.10.151

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Figure 1: Requirements on absorption and emission spectral features of the photochromic and fluorescent units...

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Figure 2: Bifunctional fluorescent-photochromic molecules 1 and 2.

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Scheme 1: Synthesis of multichromophoric glucopyranoside 2.

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Figure 3: Absorption and fluorescence spectra of compounds 6, 9, and 2 in CH₃CN: (a) absorption spectrum of 6...

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Figure 4: Absorption and fluorescence changes of compound 2 (1.0 μM in CH₃CN) upon UV–visible irradiation: (a...

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Figure 5: Partial ¹H NMR spectra of compound 2 (11 μM in CD₃CN/DMSO-d₆ 4:1) before and after increasing irrad...

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Figure 6: (a) Fluorescence decays (λ_exc = 475 nm, λ_em = 610 nm) of compound 2-OF, and 2 after irradiation at ...

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Full Research Paper

Published 30 Jun 2014

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