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Beilstein J. Org. Chem. 2025, 21, 234–241, doi:10.3762/bjoc.21.15
Graphical Abstract
Figure 1: Selected examples containing tricyclic imidazole, CF2H or PhCF2 group.
Scheme 1: Strategies for the synthesis of difluoromethylated and difluoroarylmethylated tricyclic imidazoles.
Scheme 2: Substrate scope of the protocol. Reaction conditions: 1 (0.2 mmol), 2 (1.4 mmol), and PIDA (0.8 mmo...
Scheme 3: Control experiments and plausible mechanism.
Beilstein J. Org. Chem. 2015, 11, 2721–2726, doi:10.3762/bjoc.11.293
Figure 1: Bioactive compounds containing 1,2-aminoalcohol motif.
Scheme 1: Copper-catalyzed radical aminooxygenation reaction of styrenes.
Figure 2: The copper-catalyzed three-component aminooxygenation of styrenes with NFSI and NHPI derivatives. R...
Scheme 2: The plausible mechanism.
Scheme 3: Selective reduction of the aminooxygenation product.