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Search for "benzofurans" in Full Text gives 28 result(s) in Beilstein Journal of Organic Chemistry.

Inter- and intramolecular enantioselective carbolithiation reactions

  • Asier Gómez-SanJuan,
  • Nuria Sotomayor and
  • Esther Lete

Beilstein J. Org. Chem. 2013, 9, 313–322, doi:10.3762/bjoc.9.36

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  • synthesis of chiral aromatics and heteroaromatics, such as isoquinolines or benzofurans, though lower yields and ee were obtained [15]. On the other hand, α-aryl O-(α-arylalkenyl) carbamates (α-carbamoyloxy-substituted styrenes) such as 14 undergo facile intermolecular carbolithiation reactions, via
  • using (−)-sparteine (L1) as chiral ligand, and diisopropyl ether as solvent (Scheme 17). The resulting organolithium can be trapped with several external electrophiles [50]. The presence of a substituent at the 6-position of the aromatic ring (R1 ≠ H) is necessary to obtain the benzofurans 48. Otherwise
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Published 13 Feb 2013

A novel and facile synthesis of 3-(2-benzofuroyl)- and 3,6-bis(2-benzofuroyl)carbazole derivatives

  • Wentao Gao,
  • Meiru Zheng and
  • Yang Li

Beilstein J. Org. Chem. 2011, 7, 1533–1540, doi:10.3762/bjoc.7.180

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  • (0.5 equiv) as catalyst in the presence of K2CO3 as base in refluxing CH3CN for 10 h, the desired benzofurans 3a were obtained, but the attempt was still plagued by low yield. In this reaction the use of 0.5 equivalents of PEG-400 was found most suitable with 1 and 2a to provide a maximum yield of 3a
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Published 17 Nov 2011

First synthesis of 2-(benzofuran-2-yl)-6,7-methylene dioxyquinoline-3-carboxylic acid derivatives

  • Wentao Gao,
  • Jia Liu,
  • Yun Jiang and
  • Yang Li

Beilstein J. Org. Chem. 2011, 7, 210–217, doi:10.3762/bjoc.7.28

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  • construction of the benzofuran moiety from intermediate 5. For the construction of 2-substituted benzofurans, the most widely used approach involves the palladium-catalyzed heteroannulation of 2-halophenols with a terminal alkyne via a tandem Sonogashira coupling-5-endo-dig-cyclization, largely based on the
  • methods of Larock and his co-workers [31][32][33][34]. Recently, others less popular approaches for the synthesis of 2-substituted benzofurans have included p-toluenesulfonic acid-mediated cyclization of o-(1-alkynyl)anisoles to obtain 2-arylsubstituted benzofurans [35], rearrangement and cyclization
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Published 15 Feb 2011
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