New modification of the Perkow reaction: halocarboxylate anions as leaving groups in 3-acyloxyquinoline- 2,4(1H,3H)-dione compounds

• Oldřich Paleta,
• Karel Pomeisl,
• Stanislav Kafka,
• Antonín Klásek and
• Vladislav Kubelka

Beilstein J. Org. Chem. 2005, 1, No. 17, doi:10.1186/1860-5397-1-17

• formation of product 9 is depicted in Scheme 5. An analogous mechanism featuring fluoride anion as a leaving group was proposed previously for the reaction of perfluorinated aliphatic ketones with trialkyl phosphites. [7] The products 8 and 9 were obtained in isolated yields of 18–68% and 11–38% (Table 1