Synthesis of trifunctional cyclo-β-tripeptide templates

• Frank Stein,
• Tahir Mehmood,
• Tilman Plass,
• Javid H. Zaidi and
• Ulf Diederichsen

Beilstein J. Org. Chem. 2012, 8, 1576–1583, doi:10.3762/bjoc.8.180

• aluminium sheets silica gel 60 F254. Detection was performed under UV light (254 nm) or by dipping into a solution of ninhydrin (3% in ethanol) followed by heating with a heat gun. Eluents and the appropriate Rf values are indicated. The columns for flash chromatography were packed with silica gel 60 from

Molecular rearrangements of superelectrophiles

• Douglas A. Klumpp

Beilstein J. Org. Chem. 2011, 7, 346–363, doi:10.3762/bjoc.7.45

• ring closure steps. For example, ninhydrin (28) was shown [18] to give condensation products with arenes in acid-promoted reactions. In H2SO4, the product 29 is obtained via a simple condensation reaction at the C-2 gem-diol group (Scheme 5). When superacidic CF3SO3H is used, ninhydrin yields 3

• . Condensations of ninhydrin (28) with benzene. Rearrangement of 29 to 30. Superacid promoted ring opening of succinic anhydride (33). Reaction of phthalic acid (36) in FSO3H-SbF5. Ring expansion of superelectrophile 42. Reaction of camphor (44) in superacid. Isomerization of 2-cyclohexen-1-one (48

Hybrid biofunctional nanostructures as stimuli-responsive catalytic systems

• Gernot U. Marten,
• Thorsten Gelbrich and
• Annette M. Schmidt

Beilstein J. Org. Chem. 2010, 6, 922–931, doi:10.3762/bjoc.6.98

• ) (Aldrich, 98%), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) (ABCR, 98%), N-hydroxy succinimide (NHS, Fluka), iron(III) chloride hexahydrate, iron(II) chloride tetrahydrate (Fluka, 98%), ninhydrin (Riedel-de-Haen), oligo(ethylene glycol) methylether methacrylate (OEGMA, Aldrich, Mn

Enantiospecific synthesis of [2.2]paracyclophane- 4-thiol and derivatives

• Gareth J. Rowlands and
• Richard J. Seacome

Beilstein J. Org. Chem. 2009, 5, No. 9, doi:10.3762/bjoc.5.9

• ethanolic vanillin, aqueous potassium manganate(VII), ninhydrin or acidic anisaldehyde as appropriate. Petrol refers to redistilled petroleum ether (60–80 °C), and ether to diethyl ether. Ether and THF were distilled from sodium-benzophenone ketyl, toluene from 4Å molecular sieves or calcium chloride

Synthesis of new C^α-tetrasubstituted α-amino acids

• Andreas A. Grauer and
• Burkhard König

Beilstein J. Org. Chem. 2009, 5, No. 5, doi:10.3762/bjoc.5.5

• before use. Silica gel 60 (230–400 mesh) was used for column chromatography. TLC was carried out with silica gel 60 F254 plates. Visualization was accomplished by UV light and ninhydrin staining. All NMR spectra were recorded on a Bruker Avance 300 (300 MHz) instrument with external standard. For NMR