Homolytic substitution at phosphorus for C–P bond formation in organic synthesis

• Hideki Yorimitsu

Beilstein J. Org. Chem. 2013, 9, 1269–1277, doi:10.3762/bjoc.9.143

• Hideki Yorimitsu Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan ACT-C, Japan Science and Technology Agency, Sakyo-ku, Kyoto 606-8502, Japan 10.3762/bjoc.9.143 Abstract Organophosphorus compounds are important in organic chemistry. This

• review article covers emerging, powerful synthetic approaches to organophosphorus compounds by homolytic substitution at phosphorus with a carbon-centered radical. Phosphination reagents include diphosphines, chalcogenophosphines and stannylphosphines, which bear a weak P–heteroatom bond for homolysis

• . This article deals with two transformations, radical phosphination by addition across unsaturated C–C bonds and substitution of organic halides. Keywords: addition; free radical; homolysis; phosphine; radical; substitution; Introduction Organophosphorus compounds constitute an important class of

Asymmetric Diels–Alder reaction with >C=P– functionality of the 2-phosphaindolizine-η¹-P-aluminium(O-menthoxy) dichloride complex: experimental and theoretical results

• Rajendra K. Jangid,
• Nidhi Sogani,
• Neelima Gupta,
• Raj K. Bansal,
• Moritz von Hopffgarten and
• Gernot Frenking

Beilstein J. Org. Chem. 2013, 9, 392–400, doi:10.3762/bjoc.9.40

• phosphinine [15]. We recently compiled a review on the DA reactions involving the >C=P– functionality of various organophosphorus compounds wherein all these aspects have been discussed [16]. During the past few years, we have investigated the DA reaction with the >C=P– functionality of 1,3-azaphospholes

Valence isomerization of cyclohepta-1,3,5-triene and its heteroelement analogues

• Helen Jansen,
• J. Chris Slootweg and
• Koop Lammertsma

Beilstein J. Org. Chem. 2011, 7, 1713–1721, doi:10.3762/bjoc.7.201

• +G(d,p) level [7]. Also for the phosphepine system [108], benzannulation leads to interesting targets. Namely, the thermal lability of the transition-metal-complexed 3H-benzophosphepine 33 was explored by Lammertsma et al. for the synthesis of a variety of organophosphorus compounds by means of [1

Synthesis of phosphorothioates using thiophosphate salts

• Babak Kaboudin and
• Fatemeh Farjadian

Beilstein J. Org. Chem. 2006, 2, No. 4, doi:10.1186/1860-5397-2-4

• alumina under solvent-free conditions using microwave irradiation. Introduction Organophosphorus compounds have found a wide range of application in the areas of industrial, agricultural, and medicinal chemistry owing to their biological and physical properties as well as their utility as synthetic

• the utility of surface-mediated reactions for the synthesis of organophosphorus compounds, [37][38][39][40][41][42][43][44][45][46][47][48] we report a new method for the preparation of phosphorothioates by reaction of diethyl phosphite with alkyl halides in the presence of a mixture of ammonium

• group (hard electrophilic center) gives the O-acylation product. As a part of our efforts to explore the utility of surface-mediated reactions for the synthesis of organophosphorus compounds, [16][17][18] herein we report a new method for the preparation of phosphorothioates by reaction of diethyl