2-Phenyl- tetrahydropyrimidine- 4(1H)-ones – cyclic benzaldehyde aminals as precursors for functionalised β²-amino acids

• Markus Nahrwold,
• Arvydas Stončius,
• Anna Penner,
• Beate Neumann,
• Hans-Georg Stammler and
• Norbert Sewald

Beilstein J. Org. Chem. 2009, 5, No. 43, doi:10.3762/bjoc.5.43

• employed in peptide chemistry as asparagine protective groups [52] and as proline mimetics [40]. The class of compounds described in this paper can therefore be considered as a versatile tool in peptide and amino acid chemistry. X-ray crystal structure of 10 [44]. Comparison of coupling constants (C5–C6