Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.0^2,6]decane skeleton

• Matthias Breuning,
• Tobias Häuser,
• Christian Mehler,
• Christian Däschlein,
• Carsten Strohmann,
• Andreas Oechsner and
• Holger Braunschweig

Beilstein J. Org. Chem. 2009, 5, No. 81, doi:10.3762/bjoc.5.81

• β-turn-inducing building blocks in peptidomimetics and for chiral auxiliaries in asymmetric organocatalysis. Keywords: amino acid; enantioselective synthesis; norbornane; polycyclic compounds; pyrrolidine; Introduction Unnatural amino acids with a rigid bowl-shaped backbone have received

Synthesis and Diels–Alder cycloaddition reaction of norbornadiene and benzonorbornadiene dimers

• Bilal Nişancı,
• Erdin Dalkılıç,
• Murat Güney and
• Arif Daştan

Beilstein J. Org. Chem. 2009, 5, No. 39, doi:10.3762/bjoc.5.39

• orientation) also confirms the exo structures for 11, 12, 18 and 19 (Figure 1). In summary, the synthesis and cycloaddition reaction of norbornadiene and benzonorbornadiene dimers was investigated and new norbornanoid polycyclic compounds, which open up several synthetic and mechanical investigations, were

New modification of the Perkow reaction: halocarboxylate anions as leaving groups in 3-acyloxyquinoline- 2,4(1H,3H)-dione compounds

• Oldřich Paleta,
• Karel Pomeisl,
• Stanislav Kafka,
• Antonín Klásek and
• Vladislav Kubelka

Beilstein J. Org. Chem. 2005, 1, No. 17, doi:10.1186/1860-5397-1-17

• , amides or acyl halides. [5][6] Examples of the successful Perkow reaction also include chlorofluoro ketones, e.g. 1,3-dichloro-1,1,3,3-tetrafluoroacetone,[7] α-halonitroalkanes, and in rare cases also polycyclic compounds[8] such as 3,3-dichloro-1-methylquinoline-2,4(1H,3H)-dione. [9] In the Perkow