Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663

• Orwah Saleh,
• Katrin Flinspach,
• Lucia Westrich,
• Andreas Kulik,
• Bertolt Gust,
• Hans-Peter Fiedler and
• Lutz Heide

Beilstein J. Org. Chem. 2012, 8, 501–513, doi:10.3762/bjoc.8.57

• identified in nearly all investigated bacterial strains that produce phenazine compounds [3][6]. Other genes have been shown to play a role in the regulation of phenazine biosynthesis. In P. fluorescens, the transcriptional regulation involves the quorum sensing proteins PhzR/PhzI, the positive two-component