Cascade alkylarylation of substituted N-allylbenzamides for the construction of dihydroisoquinolin-1(2H)-ones and isoquinoline-1,3(2H,4H)-diones

• Ping Qian,
• Bingnan Du,
• Wei Jiao,
• Haibo Mei,
• Jianlin Han and
• Yi Pan

Beilstein J. Org. Chem. 2016, 12, 301–308, doi:10.3762/bjoc.12.32

• [18][19], decarboxylative alkenylation of cycloalkanes with aryl vinylic carboxylic acids [20][21], trifluoromethylthiolation [22], thiolation [23][24], alkenylation [25][26], dehydrogenation−olefination and esterification [27][28], radical addition/1,2-aryl migration [29], cascade alkylation

Chemistry of polyhalogenated nitrobutadienes, 14: Efficient synthesis of functionalized (Z)-2-allylidenethiazolidin-4-ones

• Viktor A. Zapol’skii,
• Jan C. Namyslo,
• Mimoza Gjikaj and
• Dieter E. Kaufmann

Beilstein J. Org. Chem. 2014, 10, 1638–1644, doi:10.3762/bjoc.10.170

• thiazolidinone atropisomers, due to hindered rotation between the trichlorovinyl and the arylamino groups. X-ray analysis proved the Z-configuration of the nitrovinylidene group of 11. Subsequent reactions of the thiazolidinones, such as the SNVin thiolation in 2-position of the allylidene backbone, Knoevenagel

The regulation and biosynthesis of antimycins

• Ryan F. Seipke and
• Matthew I. Hutchings

Beilstein J. Org. Chem. 2013, 9, 2556–2563, doi:10.3762/bjoc.9.290

• . griseoflavus Tü4000, which truncates the truncates C1 of AntC into a discrete protein. CCR, crotonyl-CoA reductase. Proposed biosynthetic pathway for antimycins. The antimycin biosynthetic pathway is described in detail in the text. C = condensation; A, adenylation; T, thiolation; KR, ketoreduction; KS

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

• Marcus Baumann and
• Ian R. Baxendale

Beilstein J. Org. Chem. 2013, 9, 2265–2319, doi:10.3762/bjoc.9.265

Synthesis, electronic properties and self-assembly on Au{111} of thiolated (oligo)phenothiazines

• Adam W. Franz,
• Svetlana Stoycheva,
• Michael Himmelhaus and
• Thomas J. J. Müller

Beilstein J. Org. Chem. 2010, 6, No. 72, doi:10.3762/bjoc.6.72

• sulfur, followed by stirring for 5 min at −78 °C, and the addition of freshly distilled acetyl chloride furnished the desired (oligo)phenothiazinyl thioacetates 2 and 4 in moderate to good yields (Scheme 1). However, in the case of dyad 1c thiolation was only accomplished by addition of acetylsulfur