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Search for "thiolation" in Full Text gives 32 result(s) in Beilstein Journal of Organic Chemistry.

Transition-metal-catalyzed synthesis of phenols and aryl thiols

  • Yajun Liu,
  • Shasha Liu and
  • Yan Xiao

Beilstein J. Org. Chem. 2017, 13, 589–611, doi:10.3762/bjoc.13.58

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  • succeeded in a Nickel catalyzed thiolation of aryl iodides with thiourea in DMF. Aryl iodides firstly reacted with thiourea in the presence of bis(triethylphosphine)nickel(II) chloride and sodium cyanoborohydride as catalyst precusor, and afforded aryl isothiuronium iodide, which could be further converted
  • with TBAF. In 2011, the Fu and Guo group reported that Pd(OAc)2/X-Phos (L16) and Pd2(dba)3/X-Phos-catalyzed thiolation of aryl bromide and chloride using sodium thiosulfate as thiol source [101]. The coupling reaction proceeded in water in the presence of Cs2CO3, and first gave aryl thiosulfate, which
  • catalyzed thiolation of aryl halides have been extensively studied. In 2006, the Sawada group reported that aryl iodides could couple with thiobenzoic acid in the presence of a copper catalyst and 1,10-phenanthroline (L17), affording S-aryl thiocarboxylates in excellent yields [102]. The coupled product was
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Published 23 Mar 2017

Development of a continuous process for α-thio-β-chloroacrylamide synthesis with enhanced control of a cascade transformation

  • Olga C. Dennehy,
  • Valérie M. Y. Cacheux,
  • Benjamin J. Deadman,
  • Denis Lynch,
  • Stuart G. Collins,
  • Humphrey A. Moynihan and
  • Anita R. Maguire

Beilstein J. Org. Chem. 2016, 12, 2511–2522, doi:10.3762/bjoc.12.246

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  • , the possibility of telescoping the amide formation and thiolation steps was considered. Attempts were made to use triethylamine as the base in a continuous thiolation reaction, however, the reaction was found to progress slowly and a maximum conversion of 39% was observed by 1H NMR spectroscopy
  • envisaged that flowing the reaction through a heated section of tubing would be analogous to the batch ‘hot plunge’ method but with the capacity for faster heating of the reaction. Given the superior performance of α-thioamide 2 synthesis in batch, the potential telescoping of the thiolation process with
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Published 24 Nov 2016

Cascade alkylarylation of substituted N-allylbenzamides for the construction of dihydroisoquinolin-1(2H)-ones and isoquinoline-1,3(2H,4H)-diones

  • Ping Qian,
  • Bingnan Du,
  • Wei Jiao,
  • Haibo Mei,
  • Jianlin Han and
  • Yi Pan

Beilstein J. Org. Chem. 2016, 12, 301–308, doi:10.3762/bjoc.12.32

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  • [18][19], decarboxylative alkenylation of cycloalkanes with aryl vinylic carboxylic acids [20][21], trifluoromethylthiolation [22], thiolation [23][24], alkenylation [25][26], dehydrogenation−olefination and esterification [27][28], radical addition/1,2-aryl migration [29], cascade alkylation
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Published 17 Feb 2016

Chemistry of polyhalogenated nitrobutadienes, 14: Efficient synthesis of functionalized (Z)-2-allylidenethiazolidin-4-ones

  • Viktor A. Zapol’skii,
  • Jan C. Namyslo,
  • Mimoza Gjikaj and
  • Dieter E. Kaufmann

Beilstein J. Org. Chem. 2014, 10, 1638–1644, doi:10.3762/bjoc.10.170

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  • thiazolidinone atropisomers, due to hindered rotation between the trichlorovinyl and the arylamino groups. X-ray analysis proved the Z-configuration of the nitrovinylidene group of 11. Subsequent reactions of the thiazolidinones, such as the SNVin thiolation in 2-position of the allylidene backbone, Knoevenagel
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Published 17 Jul 2014

The regulation and biosynthesis of antimycins

  • Ryan F. Seipke and
  • Matthew I. Hutchings

Beilstein J. Org. Chem. 2013, 9, 2556–2563, doi:10.3762/bjoc.9.290

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  • . griseoflavus Tü4000, which truncates the truncates C1 of AntC into a discrete protein. CCR, crotonyl-CoA reductase. Proposed biosynthetic pathway for antimycins. The antimycin biosynthetic pathway is described in detail in the text. C = condensation; A, adenylation; T, thiolation; KR, ketoreduction; KS
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Published 19 Nov 2013

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

  • Marcus Baumann and
  • Ian R. Baxendale

Beilstein J. Org. Chem. 2013, 9, 2265–2319, doi:10.3762/bjoc.9.265

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Published 30 Oct 2013

Synthesis, electronic properties and self-assembly on Au{111} of thiolated (oligo)phenothiazines

  • Adam W. Franz,
  • Svetlana Stoycheva,
  • Michael Himmelhaus and
  • Thomas J. J. Müller

Beilstein J. Org. Chem. 2010, 6, No. 72, doi:10.3762/bjoc.6.72

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  • sulfur, followed by stirring for 5 min at −78 °C, and the addition of freshly distilled acetyl chloride furnished the desired (oligo)phenothiazinyl thioacetates 2 and 4 in moderate to good yields (Scheme 1). However, in the case of dyad 1c thiolation was only accomplished by addition of acetylsulfur
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Published 02 Jul 2010
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