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Search for "1,3-diketones" in Full Text gives 51 result(s) in Beilstein Journal of Organic Chemistry.

A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

  • Magnus Rueping and
  • Boris J. Nachtsheim

Beilstein J. Org. Chem. 2010, 6, No. 6, doi:10.3762/bjoc.6.6

Graphical Abstract
  • -substituted 1,3-diketones 17 and their derivatives are of great interest. Given that the alkylation typically requires stoichiometric amounts of a base and a toxic alkyl halide the development of an efficient environmentally benign route to 2-alkylated pentanediones 17a–c employing simply benzyl-, allyl- or
  • formation of a quaternary carbon atom was possible. Although the product was isolated in lower yields (Scheme 17). Subsequently this method was expanded to other nucleophiles, such as 1,3-diketones [60]. Mirroring the Bi(OTf)3-catalyzed method, Hua et al. developed a BiCl3-catalyzed synthesis of 1,1
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Published 20 Jan 2010
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