Beilstein J. Org. Chem.2009,5, No. 19, doi:10.3762/bjoc.5.19
reproducibility due to the precise control over reaction conditions in these devices. Continuous flow technology has excellent potential for the integration of a high level of automation and for the incorporation of on-demand reaction analysis. This can be advantageous for applications such as high-throughput
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Graphical Abstract
Scheme 1:
Enantioselective addition of trimethylsilyl cyanide to benzaldehyde.
Beilstein J. Org. Chem.2007,3, No. 42, doi:10.1186/1860-5397-3-42
: Experimental Section. Experimental details and full spectroscopic data for new compounds
Acknowledgements
We express appreciation to SCYNEXIS Chemistry & Automation, Inc. for financial support of this research. The NMR and mass spectra were obtained at NCSU instrumentation laboratories, which were established
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Graphical Abstract
Figure 1: N-Acyldihydropyridone 1 and indolizidine alkaloids.