Acid- mediated reactions under microfluidic conditions: A new strategy for practical synthesis of biofunctional natural products

• Katsunori Tanaka and
• Koichi Fukase

Beilstein J. Org. Chem. 2009, 5, No. 40, doi:10.3762/bjoc.5.40

• alternative to the N-phthalyl function, we also employed the C-5 azide group in sialyl donor 1b because this azide group should direct similar “fixed-dipole moment effects”, but should be easier to convert to naturally occurring N-substituents of neuraminic acids, i.e., N-acetyl or N-glycolyl groups (see